SCHEMBL7701199

SCHEMBL7701199

COc1ccc(N2C(=O)CC(=O)NC2=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 10/20 1.00
KMT2A Q03164 10/20 1.00
MAPT P10636 9/20 1.00
RAB9A P51151 1/20 1.00
L3MBTL1 Q9Y468 3/20 0.59
POLB P06746 2/20 0.59
ALDH1A1 P00352 3/20 0.57
HSD17B10 Q99714 3/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
GAA P10253 1/20 0.53
MGLL Q99685 1/20 0.51
BLM P54132 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7703374 0.83 MAPT (1.00) MEN1KMT2AMAPTRAB9AL3MBTL1
SCHEMBL125195 0.81 MAPT (1.00) MEN1KMT2AMAPTRAB9AL3MBTL1
SCHEMBL6799176 0.81 MAPT (0.68) MEN1KMT2AMAPTRAB9AL3MBTL1
SCHEMBL5120438 0.80 MEN1 (0.71) MEN1KMT2AMAPTRAB9AL3MBTL1
SCHEMBL8117138 0.79 POLB (0.67) MEN1KMT2AMAPTRAB9AL3MBTL1
SCHEMBL20020500 0.77 MEN1 (0.69) MEN1KMT2AMAPTRAB9AL3MBTL1
SCHEMBL8441345 0.77 MEN1 (1.00) MEN1KMT2AMAPTRAB9AL3MBTL1
SCHEMBL28744558 0.77 MEN1 (0.69) MEN1KMT2AMAPTRAB9AL3MBTL1
SCHEMBL125016 0.77 MEN1 (0.68) MEN1KMT2AMAPTRAB9AL3MBTL1
SCHEMBL31579482 0.76 MEN1 (0.61) MEN1KMT2AMAPTRAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022245120-A1 NOVEL COMPOUND AND COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR INHIBITING BIOFILM FORMATION OR VIRULENCE OF PATHOGENIC MICROORGANISM 부산대학교 산학협력단 2022-11-24 WO claimed
WO-2022245120-A1 NOVEL COMPOUND AND COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR INHIBITING BIOFILM FORMATION OR VIRULENCE OF PATHOGENIC MICROORGANISM 부산대학교 산학협력단 2022-11-24 WO disclosed
CN-114605408-A 5-hydroxy-1, 3-disubstituted phenyl pyrido [2,3-d ] pyrimidine compound and preparation method and application thereof 沈阳药科大学 2022-06-10 CN disclosed
US-6342339-B2 AQUEOUS DISPERSION EASTMAN KODAK COMPANY 2002-01-29 US disclosed
US-20010038979-A1 Aggregated dyes for radiation-sensitive elements HELBER MARGARET JONES (US) 2001-11-08 US disclosed
US-20010038978-A1 Aggregated dyes for radiation-sensitive elements HELBER MARGARET JONES (US) 2001-11-08 US disclosed
US-6306567-B1 WITH METHINE CONTAINING PYRIMIDINE DYE EASTMAN KODAK COMPANY 2001-10-23 US disclosed
US-6300046-B1 PHOTOGRAPHIC FILMS FOR MULTILAYER LIGHT SENSETIVE ELEMENTS WITH PYRIMIDINE CYANINE DYES EASTMAN KODAK COMPANY 2001-10-09 US disclosed
US-6291149-B1 PHOTOGRAPHIC FILMS FOR LIGHT SENSITIVE ELEMENTS AND LIGHT INSENSITIVE ELEMENTS EASTMAN KODAK COMPANY 2001-09-18 US disclosed
US-6183944-B1 SPECTRAL ABSORBANCE MAXIMUM BATHOCHROMICALLY SHIFTED AND EXHIBITS AN UNUSUALLY HIGH EXTINCTION COEFFICIENT AND AN EXCEPTIONALLY NARROW HALFBANDWIDTH RELATIVE TO ITS NON-AGGREGATED SOLUTION ABSORBANCE SPECTRUM; PHOTOGRAPHY EASTMAN KODAK COMPANY 2001-02-06 US disclosed
US-6060228-A BACKING LAYER CONTAINS A METHINE DYE HAVING SPECIFIC MAXIMUM ABSORPTION WAVELENGTH FUJI PHOTO FILM CO., LTD. (JP) 2000-05-09 US disclosed
EP-0778493-A1 Aggregated dyes for radiation-sensitive elements EASTMAN KODAK COMPANY (US) 1997-06-11 EP disclosed
US-5459265-A Oxonol dye FUJI PHOTO FILM CO., LTD. (JP) 1995-10-17 US disclosed
US-4628082-A Derivatives of azobarbituric acid or salts or complexes thereof BAYER AKTIENGESELLSCHAFT (DE) 1986-12-09 US disclosed
US-4480097-A Isoindoline colorants BASF AKTIENGESELLSCHAFT (DE) 1984-10-30 US disclosed