Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5614088 | 1.00 | IMPDH2 (0.63) | IMPDH2 | |
| SCHEMBL5524837 | 0.85 | IMPDH2 (0.64) | IMPDH2 | |
| SCHEMBL1476207 | 0.84 | IMPDH2 (0.65) | IMPDH2 | |
| SCHEMBL1476206 | 0.84 | IMPDH2 (0.65) | IMPDH2 | |
| SCHEMBL5013949 | 0.84 | IMPDH2 (0.61) | IMPDH2 | |
| SCHEMBL5013948 | 0.84 | IMPDH2 (0.61) | IMPDH2 | |
| SCHEMBL1473510 | 0.83 | IMPDH2 (0.67) | IMPDH2 | |
| SCHEMBL1473512 | 0.83 | IMPDH2 (0.67) | IMPDH2 | |
| SCHEMBL5529880 | 0.83 | IMPDH2 (0.84) | IMPDH2 | |
| SCHEMBL1474349 | 0.82 | IMPDH2 (0.66) | IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2803357-A2 | Angiogenesis inhibitors | THE JOHNS-HOPKINS UNIVERSITY (US) | 2014-11-19 | — | — | EP | disclosed |