SCHEMBL16239668

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16239010	0.88	P2RX4 (0.49)	P2RX4MEN1MAPTKMT2ABRD4
	SCHEMBL16239312	0.82	P2RX4 (0.72)	P2RX4
	SCHEMBL16238983	0.79	P2RX4 (0.57)	P2RX4MEN1LMNAMAPTKMT2A
	SCHEMBL30094417	0.79	P2RX4 (0.57)	P2RX4MEN1LMNAMAPTKMT2A
	SCHEMBL14972514	0.79	P2RX4 (0.47)	P2RX4BRD4CREBBPNR1I3DRD2
	SCHEMBL16239039	0.77	MAPT (0.56)	P2RX4MEN1LMNAMAPTKMT2A
	SCHEMBL16239200	0.75	MAPT (0.46)	P2RX4MEN1MAPTKMT2ABRD4
	SCHEMBL28393294	0.73	MAPT (0.42)	P2RX4MEN1LMNAMAPTKMT2A
	SCHEMBL14972870	0.73	P2RX4 (0.44)	P2RX4MEN1MAPTKMT2ABRD4
	SCHEMBL16239091	0.71	P2RX4 (0.59)	P2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.