Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 12/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16239039 | 0.75 | MAPT (0.56) | MAPTMEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL16239668 | 0.73 | P2RX4 (0.48) | MAPTMEN1KMT2ALMNAP2RX4 | |
| SCHEMBL16239116 | 0.72 | P2RX4 (0.56) | MAPTMEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL16238983 | 0.66 | P2RX4 (0.57) | MAPTMEN1KMT2ALMNAP2RX4 | |
| SCHEMBL30094417 | 0.66 | P2RX4 (0.57) | MAPTMEN1KMT2ALMNAP2RX4 | |
| SCHEMBL28425415 | 0.64 | MAPT (0.44) | MAPTMEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL8956337 | 0.63 | ALDH1A1 (0.48) | MEN1KMT2ALMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL11035766 | 0.61 | MAPT (1.00) | MAPTMEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL16239054 | 0.61 | MAPT (0.52) | MAPTMEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL26933630 | 0.61 | P2RX4 (0.53) | MAPTMEN1KMT2ALMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863959-B | P2X4 receptor antagonists | 日本化学药品株式会社 | 2021-11-30 | — | — | CN | disclosed |
| CN-111333588-A | P2X4 receptor antagonists | 日本化学药品株式会社 | 2020-06-26 | — | — | CN | disclosed |
| CN-104066724-B | P2X4 receptor antagonists | 日本化学药品株式会社 | 2020-04-17 | — | — | CN | disclosed |