Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 14/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10277847 | 0.84 | TACR3 (1.00) | TACR3 | |
| SCHEMBL16239850 | 0.82 | TACR3 (0.75) | TACR3 | |
| SCHEMBL16239536 | 0.79 | TACR3 (0.74) | TACR3ALDH1A1 | |
| SCHEMBL16239696 | 0.78 | TACR3 (0.53) | TACR3ALDH1A1NR1H4HCRTR2 | |
| SCHEMBL16239826 | 0.77 | TACR3 (0.76) | TACR3 | |
| SCHEMBL16239590 | 0.76 | TACR3 (0.72) | TACR3ALDH1A1 | |
| SCHEMBL16239794 | 0.73 | TACR3 (0.71) | TACR3 | |
| SCHEMBL16239848 | 0.73 | TACR3 (0.71) | TACR3 | |
| SCHEMBL16239606 | 0.72 | TACR3 (0.62) | TACR3 | |
| SCHEMBL16239673 | 0.71 | TACR3 (0.73) | TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2661432-B1 | PYRROLIDINE DERIVATIVES AS NK3 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2014-11-19 | — | — | EP | claimed |