Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 16/20 | 0.58 |
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319570 | 0.94 | SCN9A (0.51) | SCN9AHTR2AHTR2C | |
| SCHEMBL16319802 | 0.83 | SCN9A (0.63) | SCN9A | |
| SCHEMBL365295 | 0.81 | SCN9A (0.65) | SCN9A | |
| SCHEMBL16242188 | 0.81 | SCN9A (0.55) | SCN9A | |
| SCHEMBL366512 | 0.80 | PTGER1 (0.51) | SCN9AHTR2AHTR2C | |
| SCHEMBL16319525 | 0.79 | SCN9A (0.56) | SCN9AHTR2AHTR2C | |
| SCHEMBL367459 | 0.79 | SCN9A (0.64) | SCN9A | |
| SCHEMBL366086 | 0.78 | SCN9A (0.61) | SCN9A | |
| SCHEMBL366748 | 0.78 | SCN9A (0.58) | SCN9A | |
| SCHEMBL16242238 | 0.78 | SCN9A (0.59) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593433-B1 | N-SULFONYLBENZAMIDES AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | PFIZER LTD (GB) | 2014-11-26 | — | — | EP | disclosed |