Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319570 | 0.85 | SCN9A (0.51) | SCN9A | |
| SCHEMBL16242182 | 0.83 | SCN9A (0.58) | SCN9A | |
| SCHEMBL366512 | 0.79 | PTGER1 (0.51) | SCN9A | |
| SCHEMBL16319800 | 0.79 | SCN9A (0.59) | SCN9A | |
| SCHEMBL16531731 | 0.78 | SCN9A (1.00) | SCN9A | |
| SCHEMBL16319569 | 0.78 | SCN9A (0.60) | SCN9A | |
| SCHEMBL16531159 | 0.76 | SCN9A (1.00) | SCN9A | |
| Diethylamine SCHEMBL16240132 | 0.76 | PTGER1 (0.47) | SCN9A | |
| SCHEMBL16530830 | 0.76 | SCN9A (1.00) | SCN9A | |
| SCHEMBL1092984 | 0.75 | SCN9A (1.00) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593427-B1 | SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN | PFIZER LTD (GB) | 2014-12-24 | — | — | EP | disclosed |