Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | TNKS | O95271 | 2/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.30 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811327 | 0.85 | GAA (0.33) | — | |
| SCHEMBL3814044 | 0.83 | GAA (0.34) | BTKBACE1REN | |
| SCHEMBL3059428 | 0.82 | NAAA (0.33) | EPHX2 | |
| SCHEMBL1683129 | 0.79 | GAA (0.36) | BTKBACE1 | |
| SCHEMBL3805802 | 0.78 | DDB1 (0.34) | — | |
| SCHEMBL3814397 | 0.77 | GAA (0.31) | — | |
| SCHEMBL3373246 | 0.76 | GAA (0.34) | BACE1 | |
| SCHEMBL3809696 | 0.75 | — | — | |
| SCHEMBL3369229 | 0.72 | DDB1 (0.34) | — | |
| SCHEMBL6155030 | 0.72 | POLB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086994-B1 | INHIBITORS OF HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2014-11-26 | — | — | EP | disclosed |