Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 8/20 | 0.32 |
| ▸ | ACE | P12821 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685577 | 0.89 | GAA (0.34) | GAABACE1KMT2A | |
| SCHEMBL3814044 | 0.88 | GAA (0.34) | GAABACE1BTK | |
| SCHEMBL3811327 | 0.83 | GAA (0.33) | GAA | |
| SCHEMBL3373246 | 0.80 | GAA (0.34) | GAABACE1 | |
| SCHEMBL16242435 | 0.79 | EPHX2 (0.33) | BACE1BTK | |
| SCHEMBL1655875 | 0.79 | BIRC3 (0.38) | GAA | |
| SCHEMBL3059428 | 0.79 | NAAA (0.33) | — | |
| SCHEMBL3805802 | 0.76 | DDB1 (0.34) | — | |
| SCHEMBL3814397 | 0.73 | GAA (0.31) | GAA | |
| SCHEMBL7398655 | 0.71 | GAA (0.52) | GAABACE1BTKKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305695-A2 | Macrocyclic inhibitors of Hepatitis C virus replication | Intermune, Inc. (US) | 2011-04-06 | — | — | EP | disclosed |