Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 9/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.42 |
| ▸ | AHCY | P23526 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12212793 | 1.00 | ADORA3 (0.44) | ADORA3RXFP1STING1LMNABLM | |
| SCHEMBL2404929 | 0.89 | RXFP1 (0.44) | RXFP1STING1LMNABLMKMT2A | |
| SCHEMBL5505121 | 0.87 | RXFP1 (0.43) | RXFP1STING1LMNABLMKMT2A | |
| SCHEMBL16242977 | 0.86 | RXFP1 (0.42) | RXFP1STING1LMNABLMKMT2A | |
| SCHEMBL15293690 | 0.85 | CYP1A2 (0.46) | ADORA3RXFP1STING1LMNANPSR1 | |
| SCHEMBL26882824 | 0.85 | STING1 (0.45) | ADORA3RXFP1STING1LMNABLM | |
| SCHEMBL5506122 | 0.85 | LMNA (0.51) | ADORA3RXFP1STING1LMNABLM | |
| SCHEMBL16243333 | 0.85 | RXFP1 (0.41) | RXFP1STING1LMNABLMKMT2A | |
| SCHEMBL15293689 | 0.84 | LMNA (0.44) | RXFP1STING1LMNABLMKMT2A | |
| SCHEMBL15293686 | 0.83 | RXFP1 (0.43) | RXFP1STING1LMNABLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2006293-B1 | 2'-HYDROXYL-MODIFIED RIBONUCLEOSIDE DERIVATIVE | TOKYO INST TECH (JP) | 2016-08-24 | — | — | EP | disclosed |
| US-8039611-B2 | 2′-hydroxyl group-modified ribonucleoside derivatives | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2011-10-18 | — | — | US | disclosed |
| US-20100016574-A1 | 2'-Hydroxyl Group-Modified Ribonucleoside Derivatives | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2006293-A9 | 2'-HYDROXYL-MODIFIED RIBONUCLEOSIDE DERIVATIVE | Tokyo Institute of Technology (JP) | 2009-07-22 | — | — | EP | disclosed |
| EP-2006293-A2 | 2'-HYDROXYL-MODIFIED RIBONUCLEOSIDE DERIVATIVE | Tokyo Institute of Technology (JP) | 2008-12-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016574-A1 | 2'-Hydroxyl Group-Modified Ribonucleoside Derivatives | RNASEH1, RNASEL, NSUN2 | ADORA3 1729/4885RXFP1 2049/4885STING1 1538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.