SCHEMBL1624314

SCHEMBL1624314

O=C(Oc1ccccc1)Oc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.56
TSHR P16473 2/20 0.56
POLB P06746 2/20 0.48
CYP2D6 P10635 1/20 0.48
MAPT P10636 4/20 0.45
ALDH1A1 P00352 3/20 0.45
PPARG P37231 1/20 0.45
KMT2A Q03164 1/20 0.45
NCOA2 Q15596 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
PKM P14618 1/20 0.44
SOS1 Q07889 1/20 0.44
LMNA P02545 3/20 0.43
MMP1 P03956 2/20 0.43
NT5E P21589 1/20 0.42
SNCA P37840 1/20 0.41
HTT P42858 1/20 0.41
ELANE P08246 1/20 0.41
PTGES O14684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6203459 0.92 POLB (0.50) SMN1; SMN2TSHRPOLBCYP2D6MAPT
SCHEMBL11850289 0.89 SMN1; SMN2 (0.56) SMN1; SMN2TSHRPOLBCYP2D6MAPT
SCHEMBL1687670 0.86 MAPT (0.60) SMN1; SMN2POLBMAPTALDH1A1PPARG
SCHEMBL1624304 0.83 KMT2A (0.52) MAPTALDH1A1PPARGKMT2ANCOA2
SCHEMBL9481091 0.82 PKM (0.60) SMN1; SMN2POLBMAPTALDH1A1PPARG
SCHEMBL6716602 0.82 POLB (0.53) SMN1; SMN2TSHRPOLBCYP2D6MAPT
SCHEMBL1133806 0.82 SOS1 (0.64) SMN1; SMN2TSHRPOLBCYP2D6MAPT
SCHEMBL8899186 0.81 MAPT (0.67) SMN1; SMN2TSHRMAPTALDH1A1KMT2A
SCHEMBL2490813 0.81 PARP10 (0.59) SMN1; SMN2TSHRMAPTALDH1A1KMT2A
SCHEMBL18073 0.81 TDP1 (0.54) SMN1; SMN2TSHRMAPTALDH1A1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507711-B2 Flame-retardant compound, flame-retardant particle, resin composition and resin formed body FUJI XEROX CO., LTD. (JP) 2013-08-13 US disclosed
US-8507711-B2 Flame-retardant compound, flame-retardant particle, resin composition and resin formed body FUJI XEROX CO., LTD. (JP) 2013-08-13 US disclosed
US-20120088871-A1 FLAME-RETARDANT COMPOUND, FLAME-RETARDANT PARTICLE, RESIN COMPOSITION AND RESIN FORMED BODY FUJI XEROX CO., LTD. (JP) 2012-04-12 US disclosed
US-20120088871-A1 FLAME-RETARDANT COMPOUND, FLAME-RETARDANT PARTICLE, RESIN COMPOSITION AND RESIN FORMED BODY FUJI XEROX CO., LTD. (JP) 2012-04-12 US disclosed
US-20090087659-A1 FLAME-RETARDANT COMPOUND, FLAME-RETARDANT PARTICLE, RESIN COMPOSITION AND RESIN FORMED BODY FUJI XEROX CO., LTD. (JP) 2009-04-02 US disclosed
US-20090087659-A1 FLAME-RETARDANT COMPOUND, FLAME-RETARDANT PARTICLE, RESIN COMPOSITION AND RESIN FORMED BODY FUJI XEROX CO., LTD. (JP) 2009-04-02 US disclosed
US-5644017-A SOLVENT RESISTANCE, FLAME RESISTANCE, MOLDING MATERIALS THE DOW CHEMICAL COMPANY (US) 1997-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087659-A1 FLAME-RETARDANT COMPOUND, FLAME-RETARDANT PARTICLE, RESIN COMPOSITION AND RESIN FORMED BODY GAR1, RER1, AFF1 SMN1; SMN2 797/4885TSHR 930/4885POLB 1744/4885
US-20120088871-A1 FLAME-RETARDANT COMPOUND, FLAME-RETARDANT PARTICLE, RESIN COMPOSITION AND RESIN FORMED BODY GAR1, RER1, RFT1 SMN1; SMN2 369/4885TSHR 980/4885POLB 1549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.