Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.81 |
| ▸ | CNR1 | P21554 | 6/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746942 | 0.94 | CNR2 (0.88) | CNR2CNR1TDP1 | |
| SCHEMBL14746864 | 0.93 | CNR2 (0.86) | CNR2CNR1TDP1 | |
| SCHEMBL14746878 | 0.90 | CNR2 (0.82) | CNR2CNR1TDP1 | |
| SCHEMBL14746932 | 0.90 | CNR2 (0.81) | CNR2CNR1TDP1 | |
| SCHEMBL14746929 | 0.89 | CNR2 (0.81) | CNR2CNR1TDP1 | |
| SCHEMBL3021073 | 0.89 | CNR2 (1.00) | CNR2CNR1TDP1 | |
| SCHEMBL30544878 | 0.89 | CNR2 (1.00) | CNR2CNR1TDP1 | |
| SCHEMBL14746885 | 0.88 | CNR2 (0.79) | CNR2CNR1TDP1 | |
| SCHEMBL14746853 | 0.87 | CNR2 (0.80) | CNR2CNR1TDP1 | |
| SCHEMBL674289 | 0.86 | CNR2 (1.00) | CNR2CNR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9289421-B2 | Methods and compositions for reducing serum levels of immunoglobulin E (IgE) | UNIVERSITY OF SOUTH FLORIDA (US) | 2016-03-22 | — | — | US | claimed |
| US-20140350052-A1 | Methods and Compositions for Reducing Serum Levels of Immunoglobulin E (IGE) | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-11-27 | — | — | US | claimed |
| US-9289421-B2 | Methods and compositions for reducing serum levels of immunoglobulin E (IgE) | UNIVERSITY OF SOUTH FLORIDA (US) | 2016-03-22 | — | — | US | disclosed |
| US-20140350052-A1 | Methods and Compositions for Reducing Serum Levels of Immunoglobulin E (IGE) | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-11-27 | — | — | US | disclosed |