SCHEMBL674289

SCHEMBL674289

O=C(NN1CCCCC1)c1nn(-c2ccc(Cl)cc2Cl)c2c1CCCc1cc(Cl)ccc1-2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 9/20 1.00
▸ CNR1 P21554 6/20 1.00
▸ TDP1 Q9NUW8 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29549705 1.00 CNR2 (1.00) CNR2CNR1TDP1
SCHEMBL30472028 1.00 CNR2 (1.00) CNR2CNR1TDP1
SCHEMBL14746942 0.92 CNR2 (0.88) CNR2CNR1TDP1
SCHEMBL14746864 0.91 CNR2 (0.86) CNR2CNR1TDP1
SCHEMBL3422184 0.90 CNR2 (0.88) CNR2CNR1TDP1
SCHEMBL14746878 0.87 CNR2 (0.82) CNR2CNR1TDP1
SCHEMBL14746885 0.87 CNR2 (0.79) CNR2CNR1TDP1
SCHEMBL14746932 0.86 CNR2 (0.81) CNR2CNR1TDP1
SCHEMBL14746929 0.86 CNR2 (0.81) CNR2CNR1TDP1
SCHEMBL3021073 0.86 CNR2 (1.00) CNR2CNR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2739262-B1 USE OF A CB1 RECEPTOR ANTAGONIST AS A WHITENING AND/OR ANTI-BROWNING AGENT FOR KERATIN MATERIAL OREAL (FR) 2017-09-27 — — EP claimed
EP-2739262-A2 USE OF A CB1 RECEPTOR ANTAGONIST AS A WHITENING AND/OR ANTI-BROWNING AGENT FOR KERATIN MATERIAL L'OREAL (FR) 2014-06-11 — — EP claimed
WO-2013021129-A2 USE OF A CB1 RECEPTOR ANTAGONIST AS A WHITENING AND/OR ANTI-BROWNING AGENT FOR KERATIN MATERIAL L'OREAL (FR) 2013-02-14 — — WO claimed
US-8058264-B2 Pharmaceutical compositions comprising CB1 cannabinoid receptor antagonists and potassium channel openers for the treatment of obesity and related conditions ABBOTT PRODUCTS GMBH (DE) 2011-11-15 — — US claimed
WO-2008024408-A2 PHARMACEUTICAL FORMULATIONS OF CANNABINOIDS FOR APPLICATION TO THE SKIN AND METHOD OF USE THERAQUEST BIOSCIENCES, INC. (US) 2008-02-28 — — WO claimed
WO-2008021394-A2 PHARMACEUTICAL FORMULATIONS OF CANNABINOIDS AND METHOD OF USE THERAQUEST BIOSCIENCES, LLC (US) 2008-02-21 — — WO claimed
EP-1807063-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING CB1 CANNABINOID RECEPTOR ANTAGONISTS AND POTASSIUM CHANNEL OPENERS FOR THE TREATMENT OF DIABETES MELLITUS TYPE I, OBESITY AND RELATED CONDITIONS Solvay Pharmaceuticals GmbH (DE) 2007-07-18 — — EP claimed
US-20060128673-A1 Pharmaceutical compositions comprising CB1 cannabinoid receptor antagonists and potassium channel openers for the treatment of obesity and related conditions ABBOTT PRODUCTS GMBH (DE) 2006-06-15 — — US claimed
WO-2006045799-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING CB1 CANNABINOID RECEPTOR ANTAGONISTS AND POTASSIUM CHANNEL OPENERS FOR THE TREATMENT OF DIABETES MELLITUS TYPE I, OBESITY AND RELATED CONDITIONS SOLVAY PHARMACEUTICALS GMBH (DE) 2006-05-04 — — WO claimed
EP-3746064-B1 COMPOUNDS FOR USE IN THE TREATMENT OF ACUTE BRAIN INJURY UNIV COPENHAGEN (DK) 2025-04-16 — — EP disclosed
US-20240391865-A1 COMPOUNDS FOR THE TREATMENT OF ACUTE BRAIN INJURY OTAGO INNOVATION LIMITED (NZ) 2024-11-28 — — US disclosed
US-12077495-B2 Compounds for the treatment of acute brain injury Københavns Universitet (DK) 2024-09-03 — — US disclosed
US-20230172874-A1 USE OF CANNABIDIOL FOR THE TREATMENT OF INSOMNIA ASSOCIATED TO PAIN GOBBI GABRIELLA (CA) 2023-06-08 — — US disclosed
US-20210122700-A1 COMPOUNDS FOR THE TREATMENT OF ACUTE BRAIN INJURY UNIVERSITY OF OTAGO (NZ) 2021-04-29 — — US disclosed
US-20070254863-A1 Use of CBx cannabinoid receptor modulators as potassium channel modulators SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-01 — — US disclosed
US-20070254863-A1 Use of CBx cannabinoid receptor modulators as potassium channel modulators SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-01 — — US disclosed
US-20070254862-A1 Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-01 — — US disclosed
EP-1807063-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING CB1 CANNABINOID RECEPTOR ANTAGONISTS AND POTASSIUM CHANNEL OPENERS FOR THE TREATMENT OF DIABETES MELLITUS TYPE I, OBESITY AND RELATED CONDITIONS Solvay Pharmaceuticals GmbH (DE) 2007-07-18 — — EP disclosed
US-20060128673-A1 Pharmaceutical compositions comprising CB1 cannabinoid receptor antagonists and potassium channel openers for the treatment of obesity and related conditions ABBOTT PRODUCTS GMBH (DE) 2006-06-15 — — US disclosed
WO-2006045799-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING CB1 CANNABINOID RECEPTOR ANTAGONISTS AND POTASSIUM CHANNEL OPENERS FOR THE TREATMENT OF DIABETES MELLITUS TYPE I, OBESITY AND RELATED CONDITIONS SOLVAY PHARMACEUTICALS GMBH (DE) 2006-05-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12077495-B2 Compounds for the treatment of acute brain injury F2R, F2RL3, ARG2 CNR2 336/4885CNR1 232/4885TDP1 3895/4885
US-20210122700-A1 COMPOUNDS FOR THE TREATMENT OF ACUTE BRAIN INJURY F2R, F2RL3, ARG2 CNR2 349/4885CNR1 260/4885TDP1 3992/4885
US-20070254863-A1 Use of CBx cannabinoid receptor modulators as potassium channel modulators CNR2, CNR1, KCNN1 CNR2 1/4885CNR1 2/4885TDP1 3902/4885
US-20060128673-A1 Pharmaceutical compositions comprising CB1 cannabinoid receptor antagonists and potassium channel openers for the treatment of obesity and related conditions CNR1, CNR2, KCNJ11 CNR2 2/4885CNR1 1/4885TDP1 4645/4885
US-20240391865-A1 COMPOUNDS FOR THE TREATMENT OF ACUTE BRAIN INJURY F2R, F2RL3, ARG2 CNR2 349/4885CNR1 260/4885TDP1 3992/4885
US-20070254862-A1 Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators CNR1, CNR2, KCNJ11 CNR2 2/4885CNR1 1/4885TDP1 3877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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