Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.30 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | LGMN | Q99538 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318609 | 0.88 | MAPT (0.41) | PTGDR2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL2318721 | 0.85 | MTOR (0.34) | PTGDR2ALDH3A1CXCL8GAANOD2 | |
| SCHEMBL2317810 | 0.84 | ALDH1A1 (0.36) | SYKALDH1A1HTTHSD17B10MEN1 | |
| SCHEMBL16245259 | 0.84 | PIK3CA (0.37) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL2316443 | 0.83 | ESRRG (0.38) | ALDH1A1HTT | |
| SCHEMBL2317311 | 0.83 | EED (0.34) | ALDH3A1NOD2NOD1LGMN | |
| SCHEMBL16245234 | 0.82 | NR1H3 (0.36) | SYKALDH3A1ALDH1A1NPSR1NR1H2 | |
| SCHEMBL1932784 | 0.81 | PTGDR2 (0.34) | PTGDR2ALDH3A1ALDH1A1HPGDHTT | |
| SCHEMBL2317026 | 0.80 | KDM4E (0.42) | ALDH1A1MEN1KMT2ANPSR1GAA | |
| SCHEMBL2318630 | 0.80 | CD274 (0.46) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140349970-A1 | NOVEL TRICYCLIC COMPOUNDS | ABBVIE INC. (US) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140349970-A1 | NOVEL TRICYCLIC COMPOUNDS | CCNI, IL2, IL4I1 | PTGDR2 237/4885SYK 1996/4885ALDH3A1 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.