Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968926 | 0.84 | APP (0.47) | PKMLMNACA12CA1CA2 | |
| SCHEMBL5959273 | 0.84 | ALOX5 (0.64) | PKMLMNACA12CA1CA2 | |
| SCHEMBL3968930 | 0.84 | APP (0.47) | PKMLMNACA12CA1CA2 | |
| SCHEMBL5959270 | 0.84 | ALOX5 (0.64) | PKMLMNACA12CA1CA2 | |
| SCHEMBL5030552 | 0.78 | CA12 (0.56) | PKMLMNACA12CA1CA2 | |
| SCHEMBL70379 | 0.78 | ALOX5 (0.70) | PKMLMNACA12CA1CA2 | |
| Ethane SCHEMBL27660205 | 0.76 | ALOX5 (0.67) | PKMLMNACA12CA1CA2 | |
| SCHEMBL562147 | 0.76 | ERN1 (0.63) | PKMLMNACA12CA1CA2 | |
| SCHEMBL7655795 | 0.76 | ACHE (0.59) | CA9MAPTKMT2AGAAPTGS2 | |
| SCHEMBL1047550 | 0.76 | ABL1 (0.65) | PKMLMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778899-A1 | RNA-DIRECTED DNA CLEAVAGE AND GENE EDITING BY CAS9 ENZYME FROM NEISSERIA MENINGITIDIS | Northwestern University (US) | 2021-02-17 | — | — | EP | claimed |
| EP-2999788-B1 | RNA-DIRECTED DNA CLEAVAGE AND GENE EDITING BY CAS9 ENZYME FROM NEISSERIA MENINGITIDIS | UNIV NORTHWESTERN (US) | 2020-07-08 | — | — | EP | claimed |
| US-20140349405-A1 | RNA-DIRECTED DNA CLEAVAGE AND GENE EDITING BY CAS9 ENZYME FROM NEISSERIA MENINGITIDIS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-11-27 | — | — | US | claimed |
| US-20240067982-A1 | RNA-DIRECTED DNA CLEAVAGE AND GENE EDITING BY CAS9 ENZYME FROM NEISSERIA MENINGITIDIS | UNIV NORTHWESTERN (US) | 2024-02-29 | — | — | US | disclosed |
| US-20230293411-A1 | BIODEGRADABLE UV ABSORBERS | BASF SE (DE) | 2023-09-21 | — | — | US | disclosed |
| EP-4167938-A1 | BIODEGRADABLE UV ABSORBERS | BASF SE (DE) | 2023-04-26 | — | — | EP | disclosed |
| WO-2021254998-A1 | BIODEGRADABLE UV ABSORBERS | BASF SE (DE) | 2021-12-23 | — | — | WO | disclosed |
| EP-3778899-A1 | RNA-DIRECTED DNA CLEAVAGE AND GENE EDITING BY CAS9 ENZYME FROM NEISSERIA MENINGITIDIS | Northwestern University (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-2999788-B1 | RNA-DIRECTED DNA CLEAVAGE AND GENE EDITING BY CAS9 ENZYME FROM NEISSERIA MENINGITIDIS | UNIV NORTHWESTERN (US) | 2020-07-08 | — | — | EP | disclosed |
| EP-2178491-B1 | MIXTURES COMPRISING BENZOTRIAZOLES AND MEROCYANINES | BASF SE (DE) | 2017-03-22 | — | — | EP | disclosed |
| EP-2016059-B1 | TRIAZINE DERIVATIVES | BASF SE (DE) | 2016-12-07 | — | — | EP | disclosed |
| EP-2999788-A1 | RNA-DIRECTED DNA CLEAVAGE AND GENE EDITING BY CAS9 ENZYME FROM NEISSERIA MENINGITIDIS | Northwestern University (US) | 2016-03-30 | — | — | EP | disclosed |
| US-20140349405-A1 | RNA-DIRECTED DNA CLEAVAGE AND GENE EDITING BY CAS9 ENZYME FROM NEISSERIA MENINGITIDIS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-11-27 | — | — | US | disclosed |
| WO-2014190181-A1 | RNA-DIRECTED DNA CLEAVAGE AND GENE EDITING BY CAS9 ENZYME FROM NEISSERIA MENINGITIDIS | NORTHWESTERN UNIVERSITY (US) | 2014-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293411-A1 | BIODEGRADABLE UV ABSORBERS | ERCC4, ERCC1, UNG | PKM 2878/4885LMNA 1186/4885CA12 1887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.