SCHEMBL16245940

SCHEMBL16245940

C[C@H](Nc1csc2ccccc12)C(=O)O.N[C@@H](Cc1ccc(Br)cc1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 2/20 0.44
▸ SLC7A5 Q01650 2/20 0.44
▸ ALPI P09923 1/20 0.44
▸ PTGS1 P23219 1/20 0.44
▸ XIAP P98170 1/20 0.44
▸ MME P08473 3/20 0.41
▸ MAPT P10636 3/20 0.39
▸ NPC1 O15118 2/20 0.39
▸ RAB9A P51151 2/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ TPH1 P17752 2/20 0.37
▸ SDCBP O00560 1/20 0.37
▸ SDC2 P34741 1/20 0.37
▸ PTPRC P08575 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ RECQL P46063 1/20 0.36
▸ OPRM1 P35372 2/20 0.36
▸ OPRD1 P41143 2/20 0.36
▸ OPRK1 P41145 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21748385 1.00 PKM (0.44) PKMSLC7A5ALPIPTGS1XIAP
Fenclonine SCHEMBL27985739 0.89 PKM (0.44) PKMSLC7A5ALPIPTGS1XIAP
SCHEMBL29157483 0.84 MAPT (0.47) PKMMAPTNPC1RAB9AMEN1
Alanine SCHEMBL28062592 0.83 PKM (0.52) PKMMAPTNPC1RAB9A
SCHEMBL837337 0.82 PKM (0.58) PKMMAPTNPC1RAB9AALDH1A1
SCHEMBL29362649 0.82 PKM (0.58) PKMMAPTNPC1RAB9AALDH1A1
SCHEMBL29478388 0.82 PKM (0.58) PKMMAPTNPC1RAB9AALDH1A1
SCHEMBL17142326 0.82 PKM (0.58) PKMMAPTNPC1RAB9AALDH1A1
SCHEMBL173452 0.82 PKM (0.58) PKMMAPTNPC1RAB9AALDH1A1
SCHEMBL349628 0.82 PKM (0.58) PKMMAPTNPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11680088-B2 Bioactive peptides derived from snakes UNIVERSITEIT LEIDEN (NL) 2023-06-20 — — US claimed
US-12037372-B2 Bioactive peptides derived from snakes UNIVERSITEIT LEIDEN (NL) 2024-07-16 — — US disclosed
US-20240197820-A1 Bacteriocin for new application SYNGULON S.A. (BE) 2024-06-20 — — US disclosed
EP-4331622-A2 INTEGRIN BINDING PEPTIDES AND USES THEREOF Universiteit Twente (NL) 2024-03-06 — — EP disclosed
EP-4314015-A1 INHIBITORS OF THE WNT SIGNALING PATHWAY AND USES THEREOF Stichting VU (NL) 2024-02-07 — — EP disclosed
US-20240025965-A1 INTEGRIN BINDING PEPTIDES AND USES THEREOF PRAKASH JAI (NL) 2024-01-25 — — US disclosed
US-20230391839-A1 BIOACTIVE PEPTIDES DERIVED FROM SNAKES UNIV LEIDEN (NL) 2023-12-07 — — US disclosed
EP-4284812-A1 NOVEL SELECTIVE ANTIMICROBIAL FUSION PEPTIDES Bombi Biomics BV (NL) 2023-12-06 — — EP disclosed
EP-3365353-B1 INTEGRIN BINDING PEPTIDES AND USES THEREOF UNIV TWENTE (NL) 2023-11-22 — — EP disclosed
US-11680088-B2 Bioactive peptides derived from snakes UNIVERSITEIT LEIDEN (NL) 2023-06-20 — — US disclosed
US-20180312567-A1 INTEGRIN BINDING PEPTIDES AND USES THEREOF PRAKASH, JAI (NL) 2018-11-01 — — US disclosed
EP-3087092-B1 ANTIMICROBIAL PEPTIDE AND USES THEREOF ACADEMISCH ZIEKENHUIS LEIDEN (NL) 2018-07-25 — — EP disclosed
US-9562085-B2 Antimicrobial peptide ACADEMISCH ZIEKENHUIS LEIDEN H.O.D.N. LUMC (NL) 2017-02-07 — — US disclosed
US-20160317611-A1 Antimicrobial Peptide and Uses Thereof ACADEMISCH ZIEKENHUIS LEIDEN H.O.D.N. LUMC (NL) 2016-11-03 — — US disclosed
EP-3087092-A1 ANTIMICROBIAL PEPTIDE AND USES THEREOF Academisch Ziekenhuis Leiden h.o.d.n. LUMC (NL) 2016-11-02 — — EP disclosed
US-20160075749-A1 ANTIMICROBIAL PEPTIDE ACADEMISCH ZIEKENHUIS LEIDEN H.O.D.N LUMC (NL) 2016-03-17 — — US disclosed
EP-2994154-A1 ANTIMICROBIAL PEPTIDE Academisch Ziekenhuis Leiden h.o.d.n. LUMC (NL) 2016-03-16 — — EP disclosed
WO-2015099535-A1 THROMBOCIDIN-DERIVED ANTIMICROBIAL PEPTIDES ACADEMISCH ZIEKENHUIS LEIDEN H.O.D.N. LUMC (NL) 2015-07-02 — — WO disclosed
WO-2015088344-A1 ANTIMICROBIAL PEPTIDE AND USES THEREOF ACADEMISCH ZIEKENHUIS LEIDEN H.O.D.N. LUMC (NL) 2015-06-18 — — WO disclosed
WO-2014182172-A1 ANTIMICROBIAL PEPTIDE ACADEMISCH ZIEKENHUIS LEIDEN H.O.D.N. LUMC (NL) 2014-11-13 — — WO disclosed
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