Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173452 | 0.94 | PKM (0.58) | PKMMAPTRAB9ANPC1ALOX5 | |
| SCHEMBL29478388 | 0.94 | PKM (0.58) | PKMMAPTRAB9ANPC1ALOX5 | |
| SCHEMBL837337 | 0.94 | PKM (0.58) | PKMMAPTRAB9ANPC1ALOX5 | |
| SCHEMBL349628 | 0.94 | PKM (0.58) | PKMMAPTRAB9ANPC1ALOX5 | |
| SCHEMBL17142326 | 0.94 | PKM (0.58) | PKMMAPTRAB9ANPC1ALOX5 | |
| SCHEMBL29362649 | 0.94 | PKM (0.58) | PKMMAPTRAB9ANPC1ALOX5 | |
| SCHEMBL14722330 | 0.85 | PKM (0.49) | PKMMAPTRAB9ANPC1GAA | |
| SCHEMBL29157483 | 0.83 | MAPT (0.47) | PKMMAPTRAB9ANPC1ALOX5 | |
| SCHEMBL21748385 | 0.83 | PKM (0.44) | PKMMAPTRAB9ANPC1 | |
| SCHEMBL16245940 | 0.83 | PKM (0.44) | PKMMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658232-A | Methods of using interleukin-10 for treating diseases and disorders | 阿尔莫生物科技股份有限公司 | 2016-06-08 | — | — | CN | disclosed |