SCHEMBL16248010

SCHEMBL16248010

CC1(C)CC2(CC(C)(C)c3cc(Oc4ccc(N)cc4)ccc32)c2ccc(Oc3ccc(N)cc3)cc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.49
ALDH1A1 P00352 8/20 0.47
MAPT P10636 5/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MITF O75030 1/20 0.47
GAA P10253 1/20 0.47
GFER P55789 1/20 0.47
NLRP1 Q9C000 1/20 0.47
NOD2 Q9HC29 1/20 0.47
TDP1 Q9NUW8 4/20 0.47
CYP3A4 P08684 2/20 0.47
TSHR P16473 1/20 0.47
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
RXRG P48443 1/20 0.44
TEAD4 Q15561 1/20 0.44
POLB P06746 1/20 0.43
MAPK1 P28482 3/20 0.42
MAOA P21397 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29608602 0.95 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1MAPTMEN1KMT2A
SCHEMBL203793 0.95 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1MAPTMEN1KMT2A
SCHEMBL9326911 0.82 BACE1 (0.33) SMN1; SMN2ALDH1A1MAPTMEN1KMT2A
SCHEMBL29549031 0.82 BACE1 (0.33) SMN1; SMN2ALDH1A1MAPTMEN1KMT2A
SCHEMBL24684596 0.81 RXRA (0.43) SMN1; SMN2ALDH1A1MAPTMEN1KMT2A
SCHEMBL10650452 0.81 RXRA (0.43) SMN1; SMN2ALDH1A1MAPTMEN1KMT2A
SCHEMBL204909 0.81 MAOB (0.49) SMN1; SMN2ALDH1A1MAPTMEN1KMT2A
SCHEMBL29521690 0.81 MAOB (0.49) SMN1; SMN2ALDH1A1MAPTMEN1KMT2A
SCHEMBL8013533 0.81 TEAD4 (0.44) SMN1; SMN2ALDH1A1MAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL10653222 0.80 RXRA (0.43) SMN1; SMN2ALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10604628-B2 Polymer and thermosetting composition containing same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2020-03-31 US disclosed
US-20170260330-A1 Novel Polymer and Thermosetting Composition Containing Same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2017-09-14 US disclosed
US-20170260330-A1 Novel Polymer and Thermosetting Composition Containing Same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2017-09-14 US disclosed
US-9695284-B2 Polymer and thermosetting composition containing same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2017-07-04 US disclosed
US-9695284-B2 Polymer and thermosetting composition containing same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2017-07-04 US disclosed
US-20140343199-A1 Novel Polymer and Thermosetting Composition Containing Same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2014-11-20 US disclosed
US-20140343199-A1 Novel Polymer and Thermosetting Composition Containing Same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2014-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170260330-A1 Novel Polymer and Thermosetting Composition Containing Same INO80C, INCENP, PUF60 SMN1; SMN2 2686/4885ALDH1A1 3767/4885MAPT 190/4885
US-10604628-B2 Polymer and thermosetting composition containing same PARG, INO80C, INCENP SMN1; SMN2 2726/4885ALDH1A1 3687/4885MAPT 113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.