SCHEMBL16250086

SCHEMBL16250086

CC1(C)OB(c2ccc3c(c2)C2(c4ccccc4-c4ccccc42)c2ccc4c(oc5ccccc54)c2-3)OC1(C)C

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.35
CSF1R P07333 1/20 0.35
ALOX5 P09917 2/20 0.34
LPL P06858 2/20 0.33
LIPG Q9Y5X9 2/20 0.33
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
MEN1 O00255 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16855491 1.00 PGR (0.35) PGRCSF1RALOX5LPLLIPG
SCHEMBL20224581 0.99 PGR (0.35) PGRCSF1RALOX5LPLLIPG
SCHEMBL20224580 0.99 PGR (0.35) PGRCSF1RALOX5LPLLIPG
SCHEMBL18732173 0.99 PGR (0.35) PGRCSF1RALOX5LPLLIPG
SCHEMBL16491819 0.95 PGR (0.36) PGRCSF1RALOX5LPLLIPG
SCHEMBL20224572 0.94 PGR (0.35) PGRCSF1RALOX5LPLLIPG
SCHEMBL18731709 0.93 PGR (0.38) PGRCSF1RALOX5LPLLIPG
SCHEMBL16491829 0.90 CSF1R (0.37) PGRCSF1RLPLLIPGPRMT5
SCHEMBL16745234 0.90 LPL (0.36) PGRCSF1RALOX5LPLLIPG
SCHEMBL19862386 0.89 PRMT5 (0.33) PGRCSF1RLPLLIPGPRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014185751-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2014-11-20 WO disclosed