Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 8/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 4/20 | 0.40 |
| ▸ | AURKA | O14965 | 3/20 | 0.40 |
| ▸ | TEK | Q02763 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1943053 | 1.00 | P2RX3 (0.43) | P2RX3METCCNT1CDK9IDO1 | |
| SCHEMBL12035225 | 1.00 | P2RX3 (0.43) | P2RX3METCCNT1CDK9IDO1 | |
| SCHEMBL6805874 | 0.92 | MET (0.41) | P2RX3METIDO1KDRAURKA | |
| SCHEMBL1942540 | 0.92 | MET (0.41) | P2RX3METIDO1KDRAURKA | |
| SCHEMBL6805877 | 0.92 | MET (0.41) | P2RX3METIDO1KDRAURKA | |
| SCHEMBL7394071 | 0.92 | MET (0.41) | P2RX3METIDO1KDRAURKA | |
| SCHEMBL4983069 | 0.89 | P2RX3 (0.47) | P2RX3CCNT1CDK9IDO1KDM4E | |
| SCHEMBL4983074 | 0.89 | P2RX3 (0.47) | P2RX3CCNT1CDK9IDO1KDM4E | |
| SCHEMBL8348548 | 0.89 | P2RX3 (0.47) | P2RX3CCNT1CDK9IDO1KDM4E | |
| SCHEMBL16380543 | 0.89 | P2RX3 (0.47) | P2RX3CCNT1CDK9IDO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889871-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-11-18 | — | — | US | disclosed |