Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185353 | 0.88 | LMNA (0.57) | LMNAPOLBMAPTALDH1A1MEN1 | |
| SCHEMBL265248 | 0.88 | LMNA (0.57) | LMNAPOLBMAPTALDH1A1MEN1 | |
| Water SCHEMBL11590419 | 0.86 | LMNA (0.55) | LMNAPOLBMAPTALDH1A1MEN1 | |
| SCHEMBL8438349 | 0.82 | FURIN (0.52) | FURINPOLBHPGDMAPTRAB9A | |
| SCHEMBL18960361 | 0.81 | LIPE (0.47) | LMNARAB9AMEN1KMT2A | |
| SCHEMBL17487334 | 0.81 | LIPE (0.47) | LMNARAB9AMEN1KMT2A | |
| Acetic Acid SCHEMBL8202609 | 0.80 | LMNA (0.53) | LMNAPOLBRAB9AALDH1A1MEN1 | |
| SCHEMBL753409 | 0.80 | SCN9A (0.44) | LMNAHPGDMAPTALDH1A1MEN1 | |
| SCHEMBL2970975 | 0.80 | MAPT (0.62) | FURINLMNAPOLBHPGDMAPT | |
| SCHEMBL2544053 | 0.80 | SCN9A (0.44) | LMNAHPGDMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014184236-A1 | SUBSTITUTED ISOXAZOLE DERIVATIVES | BASF SE (DE) | 2014-11-20 | — | — | WO | disclosed |