Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | SCD | O00767 | 3/20 | 0.57 |
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13391954 | 0.91 | MAPT (0.58) | MAPTSCDAPPRAB9ASMN1; SMN2 | |
| SCHEMBL1983311 | 0.87 | MMP2 (0.69) | MAPTSCDAPPRAB9ASMN1; SMN2 | |
| SCHEMBL2193825 | 0.87 | APP (0.60) | MAPTSCDAPPRAB9ASMN1; SMN2 | |
| SCHEMBL2192465 | 0.86 | PLG (0.61) | MAPTSCDAPPRAB9ASMN1; SMN2 | |
| SCHEMBL2195119 | 0.85 | MAPT (0.75) | MAPTSCDAPPRAB9ASMN1; SMN2 | |
| SCHEMBL12509013 | 0.85 | SCD (0.57) | MAPTSCDAPPRAB9ASMN1; SMN2 | |
| SCHEMBL1985009 | 0.85 | SCD (0.67) | MAPTSCDAPPRAB9ASMN1; SMN2 | |
| SCHEMBL5533999 | 0.83 | MAPT (0.67) | MAPTSCDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2196699 | 0.83 | MAPT (0.66) | MAPTSCDAPPRAB9ASMN1; SMN2 | |
| SCHEMBL2192963 | 0.83 | APP (0.71) | MAPTSCDAPPRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895313-B2 | Ligands for aggregated tau molecules | WISTA LABORATORIES LTD. (SG) | 2014-11-25 | — | — | US | disclosed |