SCHEMBL162565

SCHEMBL162565

Cc1cc(C(C)(C)C)ccc1C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RXRB P28702 5/20 0.69
TDP1 Q9NUW8 1/20 0.64
NR1H4 Q96RI1 5/20 0.60
RXRA P19793 4/20 0.53
SRD5A2 P31213 1/20 0.52
EPHX2 P34913 2/20 0.48
NOTUM Q6P988 1/20 0.47
RXRG P48443 1/20 0.47
RARB P10826 1/20 0.47
RARG P13631 1/20 0.47
AKR1C2 P52895 3/20 0.46
AKR1C3 P42330 2/20 0.46
SERPINE1 P05121 1/20 0.46
AKR1C1 Q04828 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2806543 0.88 RXRB (0.59) RXRBTDP1NR1H4RXRASRD5A2
SCHEMBL30295343 0.88 RXRB (0.59) RXRBTDP1NR1H4RXRASRD5A2
SCHEMBL20556574 0.87 RXRB (0.79) RXRBTDP1NR1H4RXRASRD5A2
SCHEMBL10419228 0.86 TDP1 (0.57) RXRBTDP1NR1H4RXRASRD5A2
SCHEMBL17908058 0.86 RXRB (0.57) RXRBTDP1NR1H4RXRASRD5A2
SCHEMBL1356449 0.85 TDP1 (0.71) RXRBTDP1NR1H4RXRASRD5A2
SCHEMBL31528338 0.85 TDP1 (0.71) RXRBTDP1NR1H4RXRASRD5A2
SCHEMBL17998017 0.85 TDP1 (0.56) RXRBTDP1NR1H4RXRASRD5A2
SCHEMBL28191970 0.84 RXRB (0.58) RXRBTDP1NR1H4RXRASRD5A2
SCHEMBL1070700 0.83 TDP1 (0.79) RXRBTDP1NR1H4RXRASRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553704-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-13 CN claimed
EP-2516479-B1 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF CORP (US) 2016-04-20 EP claimed
EP-2516479-A2 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF Corporation (US) 2012-10-31 EP claimed
US-8211819-B2 Internal and external donor compounds for olefin polymerization catalysts BASF CORPORATION (US) 2012-07-03 US claimed
WO-2011084691-A2 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF CORPORATION (US) 2011-07-14 WO claimed
US-20110152481-A1 Internal and external donor compounds for olefin polymerization catalysts BASF CATALYSTS LLC (US) 2011-06-23 US claimed
EP-4511114-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN Vertex Pharmaceuticals Incorporated (US) 2025-02-26 EP disclosed
CN-119242013-A Flame retardant material, preparation method thereof and product 江苏博云塑业股份有限公司 2025-01-03 CN disclosed
CN-119081387-A Flame retardant material, preparation method and product thereof 江苏博云塑业股份有限公司 2024-12-06 CN disclosed
EP-3377473-B1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS RQX PHARMACEUTICALS INC (US) 2024-06-19 EP disclosed
EP-4371982-A2 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS RQX Pharmaceuticals, Inc. (US) 2024-05-22 EP disclosed
EP-3583096-B1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS RQX PHARMACEUTICALS INC (US) 2024-03-27 EP disclosed
US-20230382910-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED 2023-11-30 US disclosed
WO-2003084968-A1 POLYDIOXABORINES, THEIR MONOMERS AND THEIR PREPARATION NITTO DENKO CORPORATION (JP) 2003-10-16 WO disclosed
EP-0498603-B1 Olefin polymerization and copolymerization process AMOCO CORP (US) 1996-12-27 EP disclosed
EP-0736552-A2 Propylene homopolymer AMOCO CORPORATION (US) 1996-10-09 EP disclosed
US-5218052-A Increased stiffness and broadend molecular weight distribution AMOCO CORPORATION (US) 1993-06-08 US disclosed
EP-0498603-A2 Olefin polymerization and copolymerization process AMOCO CORPORATION (US) 1992-08-12 EP disclosed
US-4916470-A Image bar with electrochromic switching system XEROX CORPORATION (US) 1990-04-10 US disclosed
US-4910206-A Endotoxin induced lung injury SANDOZ PHARMACEUTICALS CORP. (US) 1990-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230382910-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN TRPV1, SCN3A, KCNN3 RXRB 2417/4885TDP1 3607/4885NR1H4 528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.