Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 14/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27794042 | 0.88 | EPHX1 (0.44) | EPHX1MEN1GAAKMT2AACHE | |
| SCHEMBL27900045 | 0.83 | EPHX1 (0.63) | EPHX1MEN1GAAKMT2AACHE | |
| SCHEMBL754326 | 0.82 | MEN1 (0.66) | EPHX1MEN1GAAKMT2ATDP1 | |
| SCHEMBL14744213 | 0.82 | MEN1 (0.66) | EPHX1MEN1GAAKMT2ATDP1 | |
| SCHEMBL16806325 | 0.80 | KDM4E (0.54) | THRBPLA2G2C | |
| SCHEMBL13631005 | 0.78 | EPHX1 (0.55) | EPHX1MEN1GAAKMT2AACHE | |
| SCHEMBL3772713 | 0.78 | THRB (0.39) | MEN1GAAKMT2ATHRB | |
| SCHEMBL22861480 | 0.77 | EPHX1 (0.50) | EPHX1MEN1GAAKMT2AACHE | |
| SCHEMBL7252127 | 0.76 | EPHX1 (0.77) | EPHX1MEN1KMT2AACHETDP1 | |
| SCHEMBL14433357 | 0.76 | EPHX1 (0.70) | EPHX1MEN1GAAKMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895516-B2 | Modified saccharides, conjugates thereof, and their manufacture | NOVARTIS AG (CH) | 2014-11-25 | — | — | US | disclosed |