Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 18/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16258377 | 0.98 | CETP (0.49) | CETPLMNAGAAHTT | |
| SCHEMBL12423599 | 0.90 | CETP (0.45) | CETP | |
| SCHEMBL10238046 | 0.90 | CETP (0.45) | CETP | |
| SCHEMBL10196405 | 0.88 | CETP (0.47) | CETP | |
| SCHEMBL12424361 | 0.88 | CETP (0.47) | CETP | |
| SCHEMBL16258380 | 0.83 | CETP (0.37) | CETPGAA | |
| SCHEMBL16258381 | 0.77 | CETP (0.46) | CETP | |
| SCHEMBL12423364 | 0.76 | CETP (0.45) | CETPLMNAGAAHTT | |
| SCHEMBL16258374 | 0.76 | CYP1A2 (0.43) | CETPLMNAGAAHTT | |
| SCHEMBL10196397 | 0.76 | CETP (0.45) | CETPLMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536733-B1 | TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION | BOEHRINGER INGELHEIM INT (DE) | 2014-11-26 | — | — | EP | disclosed |