Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 6/20 | 0.43 |
| ▸ | ACE | P12821 | 4/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 2/20 | 0.38 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16259012 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL25892959 | 0.85 | METAP2 (0.38) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL25868293 | 0.84 | METAP2 (0.37) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL25868292 | 0.84 | METAP2 (0.37) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL16260027 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL16259997 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL15824013 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL15824510 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL15846824 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL15824512 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9549911-B2 | Ginger metabolites and uses thereof | NORTH CAROLINA A&T STATE UNIVERSITY (US) | 2017-01-24 | — | — | US | disclosed |
| US-9468625-B2 | Organonitro thioether compounds and medical uses thereof | EPICENTRX, INC. (US) | 2016-10-18 | — | — | US | disclosed |
| US-20160081981-A1 | ORGANONITRO THIOETHER COMPOUNDS AND MEDICAL USES THEREOF | RADIORX, INC. | 2016-03-24 | — | — | US | disclosed |
| US-9139519-B2 | Organonitro thioether compounds and medical uses thereof | EPICENTRX, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20140349988-A1 | ORGANONITRO THIOETHER COMPOUNDS AND MEDICAL USES THEREOF | RADIORX, INC. (US) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140349988-A1 | ORGANONITRO THIOETHER COMPOUNDS AND MEDICAL USES THEREOF | SLC22A8, SLCO2A1, SLCO2B1 | ALDH1A1 1453/4885MAPT 2777/4885LMNA 4706/4885 |
| US-20160081981-A1 | ORGANONITRO THIOETHER COMPOUNDS AND MEDICAL USES THEREOF | SLC22A8, XPOT, NPM1 | ALDH1A1 2447/4885MAPT 2770/4885LMNA 4550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.