Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 2/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16259454 | 0.98 | LMNA (0.35) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL16259450 | 0.98 | LMNA (0.35) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL14510160 | 0.91 | LMNA (0.42) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL31297418 | 0.89 | LMNA (0.39) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL16259447 | 0.79 | TTR (0.40) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL16259453 | 0.79 | TTR (0.40) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL16259449 | 0.76 | CXCR4 (0.37) | CXCR4 | |
| SCHEMBL16259455 | 0.72 | — | — | |
| SCHEMBL16259452 | 0.68 | — | — | |
| SCHEMBL16259451 | 0.67 | APEX1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9085548-B2 | Pseudorotaxanes, rotaxanes and catenanes formed by metal ions templating | NATIONAL TAIWAN UNIVERSITY (TW) | 2015-07-21 | — | — | US | disclosed |
| US-9085548-B2 | Pseudorotaxanes, rotaxanes and catenanes formed by metal ions templating | NATIONAL TAIWAN UNIVERSITY (TW) | 2015-07-21 | — | — | US | disclosed |
| US-20150051393-A1 | PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING | NATIONAL TAIWAN UNIVERSITY (TW) | 2015-02-19 | — | — | US | disclosed |
| US-20150051393-A1 | PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING | NATIONAL TAIWAN UNIVERSITY (TW) | 2015-02-19 | — | — | US | disclosed |
| US-8952167-B2 | Pseudorotaxanes, rotaxanes and catenanes formed by metal ions templating | NATIONAL TAIWAN UNIVERSITY (TW) | 2015-02-10 | — | — | US | disclosed |
| US-8952167-B2 | Pseudorotaxanes, rotaxanes and catenanes formed by metal ions templating | NATIONAL TAIWAN UNIVERSITY (TW) | 2015-02-10 | — | — | US | disclosed |
| US-8927597-B2 | Compounds useful in the synthesis of halichondrin B analogs | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-01-06 | — | — | US | disclosed |
| US-20140350242-A1 | PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING | NATIONAL TAIWAN UNIVERSITY (TW) | 2014-11-27 | — | — | US | disclosed |
| US-20140350242-A1 | PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING | NATIONAL TAIWAN UNIVERSITY (TW) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051393-A1 | PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING | PCNA, TIMCC, SGTA | LMNA 4145/4885CRHBP 360/4885CRHR2 856/4885 |
| US-20140350242-A1 | PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING | PCNA, TIMCC, SGTA | LMNA 4145/4885CRHBP 360/4885CRHR2 856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.