Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MMP1 | P03956 | 2/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21593779 | 0.83 | SMN1; SMN2 (0.68) | SMN1; SMN2RAB9AKMT2AALDH1A1MMP1 | |
| SCHEMBL22881994 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9AKMT2AALDH1A1MMP1 | |
| SCHEMBL22881963 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2RAB9AKMT2AALDH1A1MMP1 | |
| SCHEMBL2385951 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2RAB9AKMT2AALDH1A1MMP1 | |
| SCHEMBL12253197 | 0.80 | SMN1; SMN2 (0.71) | SMN1; SMN2RAB9AKMT2AALDH1A1MMP1 | |
| SCHEMBL28539181 | 0.80 | SMN1; SMN2 (0.66) | SMN1; SMN2RAB9AKMT2AALDH1A1MMP1 | |
| SCHEMBL28539180 | 0.80 | SMN1; SMN2 (0.66) | SMN1; SMN2RAB9AKMT2AALDH1A1MMP1 | |
| SCHEMBL24090247 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9AKMT2AALDH1A1MMP1 | |
| SCHEMBL8741412 | 0.79 | EGFR (0.73) | SMN1; SMN2RAB9AKMT2AALDH1A1MMP1 | |
| SCHEMBL8642620 | 0.79 | KMT2A (0.61) | SMN1; SMN2RAB9AKMT2AALDH1A1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160317479-A1 | METHOD OF TREATING OR PREVENTING PAIN | NOVAREMED LTD. (IL) | 2016-11-03 | — | — | US | disclosed |
| US-20140350099-A1 | Method of Treating or Preventing Pain | NOVAREMED LTD. (IL) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350099-A1 | Method of Treating or Preventing Pain | OPRL1, CALCA, CHRM1 | SMN1; SMN2 1628/4885RAB9A 4231/4885KMT2A 2303/4885 |
| US-20160317479-A1 | METHOD OF TREATING OR PREVENTING PAIN | OPRL1, CALCA, CHRM1 | SMN1; SMN2 1628/4885RAB9A 4231/4885KMT2A 2303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.