Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.63 |
| ▸ | MMP1 | P03956 | 2/20 | 0.60 |
| ▸ | MMP2 | P08253 | 2/20 | 0.60 |
| ▸ | MMP9 | P14780 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741412 | 0.86 | EGFR (0.73) | SMN1; SMN2RAB9AKMT2AALDH1A1EGFR | |
| SCHEMBL24090247 | 0.86 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9AKMT2AALDH1A1EGFR | |
| SCHEMBL2385951 | 0.86 | SMN1; SMN2 (0.64) | SMN1; SMN2RAB9AKMT2AALDH1A1EGFR | |
| SCHEMBL7667479 | 0.86 | PLAAT5 (0.62) | SMN1; SMN2RAB9AKMT2AALDH1A1EGFR | |
| SCHEMBL22881963 | 0.86 | SMN1; SMN2 (0.64) | SMN1; SMN2RAB9AKMT2AALDH1A1EGFR | |
| SCHEMBL12253197 | 0.85 | SMN1; SMN2 (0.71) | SMN1; SMN2RAB9AKMT2AALDH1A1EGFR | |
| SCHEMBL28539181 | 0.84 | SMN1; SMN2 (0.66) | SMN1; SMN2RAB9AKMT2AALDH1A1EGFR | |
| SCHEMBL28539180 | 0.84 | SMN1; SMN2 (0.66) | SMN1; SMN2RAB9AKMT2AALDH1A1EGFR | |
| SCHEMBL16260615 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9AKMT2AALDH1A1EGFR | |
| SCHEMBL15978907 | 0.83 | KMT2A (0.51) | SMN1; SMN2RAB9AKMT2AALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210207175-A1 | COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2021-07-08 | — | — | US | disclosed |
| WO-2019238091-A1 | COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF | 中国科学院上海有机化学研究所 | 2019-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210207175-A1 | COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF | TET2, ZFX, ZFR | SMN1; SMN2 1621/4885RAB9A 3127/4885KMT2A 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.