Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588443 | 0.90 | MEN1 (0.32) | EPHX2 | |
| SCHEMBL11897853 | 0.89 | — | — | |
| SCHEMBL29300070 | 0.85 | EPHX2 (0.35) | CES1EPHX2PLA2G2C | |
| SCHEMBL9872183 | 0.84 | CES1 (0.34) | CES1EPHX2PLA2G2C | |
| SCHEMBL15823328 | 0.84 | CES1 (0.46) | CES1EPHX2PLA2G2C | |
| SCHEMBL9076724 | 0.81 | CES1 (0.38) | CES1EPHX2PLA2G2C | |
| SCHEMBL20565852 | 0.79 | APP (0.32) | — | |
| SCHEMBL16263365 | 0.78 | CES1 (0.44) | CES1EPHX2PLA2G2C | |
| SCHEMBL16263366 | 0.78 | CES1 (0.44) | CES1EPHX2PLA2G2C | |
| SCHEMBL19946677 | 0.78 | CA1 (0.33) | CES1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140350181-A1 | HYDRO-FLUOROCOMPOUNDS | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350181-A1 | HYDRO-FLUOROCOMPOUNDS | AFF4, AFF1, HAX1 | CES1 1788/4885EPHX2 248/4885PLA2G2C 1878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.