Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721096 | 0.90 | KMT2A (0.57) | KMT2ANPC1RAB9AMEN1TP53 | |
| SCHEMBL17985018 | 0.89 | KMT2A (0.56) | KMT2ANPC1RAB9AMEN1TP53 | |
| SCHEMBL10209789 | 0.87 | NPC1 (0.52) | KMT2ANPC1RAB9AMEN1TP53 | |
| Hydrochloric Acid SCHEMBL720333 | 0.86 | NPC1 (0.51) | KMT2ANPC1RAB9AMEN1TP53 | |
| SCHEMBL10224092 | 0.85 | RAB9A (0.53) | KMT2ANPC1RAB9AMEN1TP53 | |
| SCHEMBL19664789 | 0.83 | KMT2A (0.51) | KMT2ANPC1RAB9AMEN1TP53 | |
| SCHEMBL19664788 | 0.83 | KMT2A (0.51) | KMT2ANPC1RAB9AMEN1TP53 | |
| SCHEMBL19674797 | 0.83 | NPC1 (0.48) | KMT2ANPC1RAB9AMEN1TP53 | |
| SCHEMBL17984862 | 0.82 | MEN1 (0.55) | KMT2ANPC1RAB9AMEN1TP53 | |
| SCHEMBL17984866 | 0.81 | NPC1 (0.47) | KMT2ANPC1RAB9AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9162983-B2 | Reactivators of organophosphorous inhibited acetylcholinesterase | SOUTHWEST RESEARCH INSTITUTE (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140350262-A1 | Reactivators Of Organophosphorous Inhibited Acetylcholinesterase | SOUTHWEST RESEARCH INSTITUTE (US) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350262-A1 | Reactivators Of Organophosphorous Inhibited Acetylcholinesterase | ACHE, BCHE, CHAT | KMT2A 1110/4885NPC1 2387/4885RAB9A 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.