SCHEMBL16265092

SCHEMBL16265092

CN[C@H](CCC(=O)O)C(=O)C(=O)C(CCCNC(=N)N)NC(=O)[C@@H](NC(=O)C(CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C(CCSC)NC(=O)[C@H](C)NC(=O)C(CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NN[C@@H](Cc1ccccc1)C(N)=O)C(C)C

nearest known ligand 0.62

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 1/20 0.62
▸ GLP1R P43220 1/20 0.60
▸ GCGR P47871 1/20 0.60
▸ GIPR P48546 1/20 0.60
▸ IL23R Q5VWK5 11/20 0.58
▸ PTH1R Q03431 5/20 0.57
▸ GRPR P30550 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16265093 1.00 RXFP1 (0.62) RXFP1GLP1RGCGRGIPRIL23R
SCHEMBL12026383 0.92 RXFP1 (0.69) RXFP1GLP1RGCGRGIPRIL23R
SCHEMBL12026389 0.92 RXFP1 (0.69) RXFP1GLP1RGCGRGIPRIL23R
SCHEMBL12026378 0.90 IL23R (0.69) RXFP1GLP1RGCGRGIPRIL23R
SCHEMBL12026377 0.90 IL23R (0.69) RXFP1GLP1RGCGRGIPRIL23R
SCHEMBL12026379 0.88 IL23R (0.68) RXFP1IL23RPTH1R
SCHEMBL12026380 0.88 IL23R (0.68) RXFP1IL23RPTH1R
SCHEMBL16265094 0.88 IL23R (0.64) IL23R
SCHEMBL12026376 0.87 IL23R (0.69) RXFP1IL23R
SCHEMBL12026385 0.87 IL23R (0.69) RXFP1IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140349949-A1 HYALURONIC ACID CONTAINING COMPOSITIONS FOR TREATMENT OF WOUNDS, SCARS, POST-SURGICAL ADHESION FORMATION PERGAMUM AB (SE) 2014-11-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140349949-A1 HYALURONIC ACID CONTAINING COMPOSITIONS FOR TREATMENT OF WOUNDS, SCARS, POST-SURGICAL ADHESION FORMATION CD44, HDGF, FIBP RXFP1 377/4885GLP1R 1967/4885GCGR 3335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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