SCHEMBL12026379

SCHEMBL12026379

CSCCC(NC(=O)[C@H](CC(N)=O)NC(=O)C(CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)C(Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)N[C@H](C(=O)NC(CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(N)=O)C(C)C

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 18/20 0.68
▸ RXFP1 Q9HBX9 1/20 0.65
▸ PTH1R Q03431 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12026380 1.00 IL23R (0.68) IL23RRXFP1PTH1R
SCHEMBL12026385 0.99 IL23R (0.69) IL23RRXFP1
SCHEMBL12026376 0.99 IL23R (0.69) IL23RRXFP1
SCHEMBL12026389 0.96 RXFP1 (0.69) IL23RRXFP1
SCHEMBL12026383 0.96 RXFP1 (0.69) IL23RRXFP1
SCHEMBL12026378 0.94 IL23R (0.69) IL23RRXFP1
SCHEMBL12026377 0.94 IL23R (0.69) IL23RRXFP1
SCHEMBL31574199 0.90 PTH1R (0.65) IL23RRXFP1PTH1R
Penetratin SCHEMBL29356568 0.89 PTH1R (0.66) IL23RRXFP1PTH1R
SCHEMBL30869166 0.88 PTH1R (0.66) IL23RPTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110306565-A1 HYALURONIC ACID CONTAINING COMPOSITIONS FOR TREATMENT OF WOUNDS, SCARS, POST-SURGICAL ADHESION FORMATION PERGAMUM AB (SE) 2011-12-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110306565-A1 HYALURONIC ACID CONTAINING COMPOSITIONS FOR TREATMENT OF WOUNDS, SCARS, POST-SURGICAL ADHESION FORMATION CD44, FN1, HDGF IL23R 1367/4885RXFP1 322/4885PTH1R 1289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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