SCHEMBL16265258

SCHEMBL16265258

C=C(C)C(=O)Oc1ccc(C(=C(CC)CC)c2ccc(OC(=O)C(=C)C)c(OC(=O)C(=C)C)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.50
TSHR P16473 2/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 5/20 0.41
ATM Q13315 1/20 0.41
ESR1 P03372 2/20 0.38
CYP19A1 P11511 1/20 0.38
ESR2 Q92731 1/20 0.38
RECQL P46063 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PSMB1 P20618 1/20 0.36
PSMB5 P28074 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16265283 0.92 ELANE (0.46) ELANETSHRKDM4EALDH1A1GAA
SCHEMBL16265298 0.90 ELANE (0.48) ELANETSHRKDM4EALDH1A1GAA
SCHEMBL16265297 0.89 ELANE (0.50) ELANETSHRKDM4EALDH1A1GAA
SCHEMBL16265289 0.86 ELANE (0.55) ELANETSHRKDM4EALDH1A1GAA
SCHEMBL16265303 0.85 KMT2A (0.53) ELANETSHRKDM4EALDH1A1GAA
SCHEMBL16265209 0.84 ELANE (0.48) ELANETSHRKDM4EALDH1A1GAA
SCHEMBL16265255 0.83 ELANE (0.49) ELANETSHRKDM4EALDH1A1GAA
SCHEMBL15471675 0.81 ELANE (0.56) ELANETSHRKDM4EALDH1A1GAA
SCHEMBL11961821 0.81 ELANE (0.56) ELANETSHRKDM4EALDH1A1GAA
SCHEMBL16265260 0.81 THRB (0.48) ELANETSHRKDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9139672-B2 Polymerizable compound, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2015-09-22 US disclosed
US-9139672-B2 Polymerizable compound, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2015-09-22 US disclosed
US-20140346399-A1 POLYMERIZABLE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-11-27 US disclosed
US-20140346399-A1 POLYMERIZABLE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-11-27 US disclosed