SCHEMBL16265255

SCHEMBL16265255

C=C(C)C(=O)Oc1ccc(/C(CC)=C(\C)c2ccc(OC(=O)C(=C)C)c(OC(=O)C(=C)C)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.49
KMT2A Q03164 4/20 0.47
ESR1 P03372 1/20 0.47
RECQL P46063 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HIF1A Q16665 1/20 0.47
TSHR P16473 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40
RAB9A P51151 1/20 0.40
ATM Q13315 1/20 0.40
NR1I2 O75469 2/20 0.37
PTGS2 P35354 1/20 0.37
BLM P54132 1/20 0.36
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
STS P08842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16265303 0.92 KMT2A (0.53) ELANEKMT2AESR1RECQLSMN1; SMN2
SCHEMBL16265211 0.92 TSHR (0.44) ELANEKMT2AESR1RECQLSMN1; SMN2
SCHEMBL16265302 0.90 ELANE (0.47) ELANEKMT2AESR1RECQLSMN1; SMN2
SCHEMBL16265257 0.86 KMT2A (0.47) ELANEKMT2AESR1RECQLSMN1; SMN2
SCHEMBL15471675 0.86 ELANE (0.56) ELANEKMT2ATSHRKDM4EALDH1A1
SCHEMBL16265291 0.85 RAB9A (0.38) ELANEKMT2AESR1RECQLSMN1; SMN2
SCHEMBL8835772 0.84 KMT2A (0.64) ELANEKMT2AESR1RECQLSMN1; SMN2
SCHEMBL16265261 0.83 THRB (0.46) ELANEKMT2AESR1RECQLSMN1; SMN2
SCHEMBL16265258 0.83 ELANE (0.50) ELANEKMT2AESR1RECQLSMN1; SMN2
SCHEMBL16265297 0.83 ELANE (0.50) ELANEKMT2AESR1RECQLSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9139672-B2 Polymerizable compound, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2015-09-22 US disclosed
US-9139672-B2 Polymerizable compound, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2015-09-22 US disclosed
US-20140346399-A1 POLYMERIZABLE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-11-27 US disclosed
US-20140346399-A1 POLYMERIZABLE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-11-27 US disclosed