Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16265304 | 0.94 | THRB (0.47) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL16265261 | 0.91 | THRB (0.46) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL29655867 | 0.88 | ESR1 (0.66) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL2583120 | 0.88 | ESR1 (0.66) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL16265310 | 0.86 | TSHR (0.42) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL16265260 | 0.85 | THRB (0.48) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL16265313 | 0.83 | THRB (0.47) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL8835900 | 0.82 | ESR1 (0.58) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL16265259 | 0.81 | THRB (0.49) | KMT2ASMN1; SMN2THRBKDM4ETHRA | |
| SCHEMBL17461516 | 0.81 | KMT2A (0.47) | KMT2ASMN1; SMN2THRBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139672-B2 | Polymerizable compound, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2015-09-22 | — | — | US | disclosed |
| US-9139672-B2 | Polymerizable compound, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2015-09-22 | — | — | US | disclosed |
| US-20140346399-A1 | POLYMERIZABLE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2014-11-27 | — | — | US | disclosed |
| US-20140346399-A1 | POLYMERIZABLE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2014-11-27 | — | — | US | disclosed |