SCHEMBL16265271

SCHEMBL16265271

O=C(/C=C/c1ccc(OC2CCCCO2)c(OC2CCCCO2)c1)c1ccc(OC2CCCCO2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.50
PDE4B Q07343 2/20 0.48
PDE4A P27815 1/20 0.48
PDE4C Q08493 1/20 0.48
PDE4D Q08499 1/20 0.48
TNFRSF1A P19438 1/20 0.48
ABCG2 Q9UNQ0 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPT P10636 6/20 0.45
LMNA P02545 4/20 0.45
ALDH1A1 P00352 2/20 0.45
GLA P06280 1/20 0.45
POLB P06746 1/20 0.45
HPGD P15428 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
RAB9A P51151 2/20 0.44
KDM4E B2RXH2 1/20 0.44
CXCL12 P48061 1/20 0.44
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9177025 1.00 PTPN1 (0.50) PTPN1PDE4BPDE4APDE4CPDE4D
SCHEMBL5619991 0.90 MAPT (0.50) PTPN1MEN1KMT2AMAPTLMNA
SCHEMBL5619986 0.90 MAPT (0.50) PTPN1MEN1KMT2AMAPTLMNA
SCHEMBL9177615 0.89 PDE4B (0.46) PTPN1PDE4BPDE4APDE4CPDE4D
SCHEMBL25195154 0.87 PDE4B (0.45) PTPN1PDE4BPDE4APDE4CPDE4D
SCHEMBL30384030 0.87 PDE4B (0.45) PTPN1PDE4BPDE4APDE4CPDE4D
SCHEMBL11959784 0.86 ABCG2 (0.63) PTPN1PDE4BPDE4APDE4CPDE4D
SCHEMBL25192649 0.86 CYP3A4 (0.54) PTPN1MEN1KMT2AMAPTLMNA
SCHEMBL31233307 0.86 MAOB (0.53) PTPN1TNFRSF1AMEN1KMT2AMAPT
SCHEMBL5619965 0.86 MAOB (0.53) PTPN1TNFRSF1AMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
US-9139672-B2 Polymerizable compound, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2015-09-22 US disclosed
US-9139672-B2 Polymerizable compound, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2015-09-22 US disclosed
US-20140346399-A1 POLYMERIZABLE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-11-27 US disclosed
US-20140346399-A1 POLYMERIZABLE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B PTPN1 1308/4885PDE4B 2645/4885PDE4A 3506/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 PTPN1 1520/4885PDE4B 3192/4885PDE4A 3576/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 PTPN1 1520/4885PDE4B 3192/4885PDE4A 3576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.