SCHEMBL5619965

SCHEMBL5619965

O=C(/C=C/c1cccc(OC2CCCCO2)c1)c1ccc(OC2CCCCO2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.53
BCHE P06276 3/20 0.47
PTPN1 P18031 1/20 0.46
CYP1B1 Q16678 2/20 0.45
CYP1A1 P04798 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
MAPT P10636 7/20 0.44
RAB9A P51151 5/20 0.44
NPC1 O15118 4/20 0.44
KEAP1 Q14145 2/20 0.44
NFE2L2 Q16236 2/20 0.44
ALDH1A1 P00352 4/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
LMNA P02545 2/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5619972 1.00 MAOB (0.53) MAOBBCHEPTPN1CYP1B1CYP1A1
SCHEMBL31233307 1.00 MAOB (0.53) MAOBBCHEPTPN1CYP1B1CYP1A1
SCHEMBL25288277 0.93 MAOB (0.50) MAOBBCHEPTPN1CYP1B1CYP1A1
SCHEMBL5619504 0.92 BCHE (0.48) MAOBBCHEPTPN1CYP1B1CYP1A1
SCHEMBL5619511 0.92 BCHE (0.48) MAOBBCHEPTPN1CYP1B1CYP1A1
SCHEMBL3064533 0.90 ATM (0.50) MAOBPTPN1CYP1B1CYP2D6MAPT
SCHEMBL30383983 0.90 ATM (0.50) MAOBPTPN1CYP1B1CYP2D6MAPT
SCHEMBL5620395 0.90 CYP1B1 (0.53) MAOBBCHECYP1B1CYP1A1MAPT
SCHEMBL5620399 0.90 CYP1B1 (0.53) MAOBBCHECYP1B1CYP1A1MAPT
SCHEMBL5619986 0.88 MAPT (0.50) MAOBPTPN1CYP1B1CYP1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
US-7276523-B2 Aminopyridine derivatives as estrogen receptor modulators SMITHKLINE BEECHAM CORPORATION (US) 2007-10-02 US disclosed
US-7276523-B2 Aminopyridine derivatives as estrogen receptor modulators SMITHKLINE BEECHAM CORPORATION (US) 2007-10-02 US disclosed
US-7276523-B2 Aminopyridine derivatives as estrogen receptor modulators SMITHKLINE BEECHAM CORPORATION (US) 2007-10-02 US disclosed
US-20040152688-A1 Aminopyridine derivatives as estrogen receptor modulators SMITHKLINE BEECHAM CORPORATION 2004-08-05 US disclosed
WO-2002079163-A1 AMINOPYRIDINE DERIVATIVES AS ESTROGEN RECEPTOR MODULATORS SMITHKLINE BEECHAM CORPORATION (US) 2002-10-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152688-A1 Aminopyridine derivatives as estrogen receptor modulators ESR2, GPER1, ESR1 MAOB 1367/4885BCHE 1905/4885PTPN1 2606/4885
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885BCHE 588/4885PTPN1 1308/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885BCHE 465/4885PTPN1 1520/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885BCHE 465/4885PTPN1 1520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.