SCHEMBL1626528

SCHEMBL1626528

O=C=Nc1c(F)c(F)c(F)c(N=C=O)c1F

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL136454 0.97 GABRA1 (0.36) GABRA1GABRB2
SCHEMBL1989667 0.94 GABRA1 (0.37) GABRA1GABRB2
SCHEMBL4860966 0.91 GABRA1 (0.36) GABRA1GABRB2
SCHEMBL11567019 0.86 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL1627559 0.83 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL8918986 0.81 GABRA1 (0.35) GABRA1GABRB2
SCHEMBL3816245 0.81 GABRA1 (0.35) GABRA1GABRB2
SCHEMBL30492067 0.79 GABRA1 (0.30) GABRA1GABRB2
SCHEMBL1986428 0.78
SCHEMBL3460970 0.78 CYP3A4 (0.35) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333777-A4 IN SITU BULKING DEVICE PRAXIS LLC (US) 2004-04-07 EP claimed
EP-1333777-A1 IN SITU BULKING DEVICE Praxis LLC (US) 2003-08-13 EP claimed
WO-2002034160-A1 IN SITU BULKING DEVICE PRAXIS LLC (US) 2002-05-02 WO claimed
US-20020049363-A1 Situ bulking device PROMETHEAN SURGICAL DEVICES 2002-04-25 US claimed
EP-4747311-A1 PERFLUOROPOLYETHER COPOLYMERS FOR BIOMEDICAL APPLICATIONS Axoft, Inc. (US) 2026-05-27 EP disclosed
US-20250026885-A1 PERFLUOROPOLYETHER COPOLYMERS FOR BIOMEDICAL APPLICATIONS AXOFT, INC. (US) 2025-01-23 US disclosed
WO-2025019824-A1 PERFLUOROPOLYETHER COPOLYMERS FOR BIOMEDICAL APPLICATIONS AXOFT, INC. (US) 2025-01-23 WO disclosed
CN-110573193-A Sealant for genitals 三洋化成工业株式会社 2019-12-13 CN disclosed
US-8604099-B2 In situ bulking composition PROMETHEAN SURGICAL DEVICES (US) 2013-12-10 US disclosed
US-20130035415-A1 IN SITU BULKING COMPOSITION PROMETHEAN SURGICAL DEVICES (US) 2013-02-07 US disclosed
US-20110135700-A1 IN SITU BULKING COMPOSITION PROMETHEAN SURGICAL DEVICES, INC. (US) 2011-06-09 US disclosed
US-7927619-B2 In situ bulking composition PROMETHEAN SURGICAL DEVICES LLC (US) 2011-04-19 US disclosed
WO-1994008269-A1 NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS AKZO NOBEL N.V. (NL) 1994-04-14 WO disclosed
US-4914163-A HYDROLYZING REACTION PRODUCT OF DIISOCYANATE, HYDROGEN CYANIDE AND TOLIDINE DIISOCYANATE; POLYPARABANIC ACIDS TONEN SEKIYU KAGAKU KABUSHIKI KAISHA (JP) 1990-04-03 US disclosed
EP-0323219-A2 Process for preparing heterocyclic copolymers Tonen Chemical Corporation (JP) 1989-07-05 EP disclosed
US-4804691-A Method for making a biodegradable adhesive for soft living tissue RICHARDS MEDICAL COMPANY (US) 1989-02-14 US disclosed
US-RE30067-E Iminoimidazolidinedione and parabanic acid polymers containing imide groups EXXON RESEARCH & ENGINEERING CO. (US) 1979-08-07 US disclosed
US-4035404-A Cyanoformamidyl isocyanates and synthesis thereof EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-07-12 US disclosed
US-3948941-A NITRILE, FROM CARBOXYLIC ANHYDRIDES AND ISOCYANATES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-04-06 US disclosed
US-3933758-A Iminoimidazolidinedione and parabanic acid polymers containing imide groups EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-01-20 US disclosed