SCHEMBL4860966

SCHEMBL4860966

O=C=Nc1c(F)c(F)c(F)c(F)c1N=C=O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL136454 0.94 GABRA1 (0.36) GABRA1GABRB2
SCHEMBL1626528 0.91 GABRA1 (0.34) GABRA1GABRB2
SCHEMBL1989667 0.90 GABRA1 (0.37) GABRA1GABRB2
SCHEMBL11567019 0.82 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL30492067 0.82 GABRA1 (0.30) GABRA1GABRB2
SCHEMBL1986428 0.80
SCHEMBL3460970 0.80 CYP3A4 (0.35) GABRA1GABRB2
SCHEMBL8918986 0.78 GABRA1 (0.35) GABRA1GABRB2
SCHEMBL3816245 0.78 GABRA1 (0.35) GABRA1GABRB2
SCHEMBL10952512 0.75 CYP3A4 (0.32) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7358320-B2 Fluorinated reactive compositions for golf balls ACUSHNET COMPANY (US) 2008-04-15 US disclosed
US-7312298-B2 Fluorinated reactive compositions for golf balls ACUSHNET COMPANY (US) 2007-12-25 US disclosed
US-20060199938-A1 Fluorinated reactive compositions for golf balls ACUSHNET COMPANY 2006-09-07 US disclosed
US-20060199937-A1 Fluorinated reactive compositions for golf balls ACUSHNET COMPANY 2006-09-07 US disclosed
EP-0359271-B1 Crosslinkable polyurethane rubbers containing polyoxyperfluoroalkylene blocks AUSIMONT SPA (IT) 1994-03-16 EP disclosed
EP-0359272-B1 Fluorinated polyurethanes containing rubber-like polyoxyperfluoroalkylene blocks and rigid blocks AUSIMONT SPA (IT) 1993-12-08 EP disclosed
US-5043410-A Hardness and tensile strength AUSIMONT S.R.L. (IT) 1991-08-27 US disclosed
US-5026814-A Polyfluoroetherurethane copolymer AUSIMONT S.R.L. (IT) 1991-06-25 US disclosed
EP-0359272-A2 Fluorinated polyurethanes containing rubber-like polyoxyperfluoroalkylene blocks and rigid blocks AUSIMONT S.p.A. (IT) 1990-03-21 EP disclosed
EP-0359271-A2 Crosslinkable polyurethane rubbers containing polyoxyperfluoroalkylene blocks AUSIMONT S.p.A. (IT) 1990-03-21 EP disclosed
EP-0359273-A2 Fluorinated polyurethanes containing polyoxyperfluoroalkylene blocks AUSIMONT S.r.l. (IT) 1990-03-21 EP disclosed
US-4818801-A IMPROVED OXYGEN PERMEABILITY; CONTACT LENSES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-04-04 US disclosed
EP-0084406-B1 OPHTHALMIC DEVICE COMPRISING A POLYMER OF A TELECHELIC PERFLUOROPOLYETHER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-07-16 EP disclosed
EP-0084406-A1 Ophthalmic device comprising a polymer of a telechelic perfluoropolyether MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-07-27 EP disclosed
US-3972856-A LOW TEMPERATURE FLEXIBLE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-08-03 US disclosed