SCHEMBL16265302

SCHEMBL16265302

C=C(C)C(=O)Oc1ccc(/C(CCC)=C(\C)c2ccc(OC(=O)C(=C)C)c(OC(=O)C(=C)C)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.47
KMT2A Q03164 5/20 0.39
ATM Q13315 1/20 0.39
TSHR P16473 2/20 0.38
ESR1 P03372 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
RAB9A P51151 1/20 0.38
RECQL P46063 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38
ALOX15 P16050 1/20 0.36
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TOP1 P11387 2/20 0.33
MAPT P10636 1/20 0.33
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16265255 0.90 ELANE (0.49) ELANEKMT2AATMTSHRESR1
SCHEMBL16265257 0.89 KMT2A (0.47) ELANEKMT2AATMTSHRESR1
SCHEMBL8835840 0.85 ELANE (0.58) ELANEKMT2AATMESR1RECQL
SCHEMBL16265303 0.84 KMT2A (0.53) ELANEKMT2AATMTSHRESR1
SCHEMBL16265313 0.84 THRB (0.47) KMT2ATSHRESR1KDM4EALDH1A1
SCHEMBL15471675 0.84 ELANE (0.56) ELANEKMT2AATMTSHRKDM4E
SCHEMBL16265209 0.84 ELANE (0.48) ELANEKMT2AATMTSHRESR1
SCHEMBL16265298 0.84 ELANE (0.48) ELANEKMT2AATMTSHRESR1
SCHEMBL16265283 0.81 ELANE (0.46) ELANEKMT2AATMTSHRESR1
SCHEMBL16265211 0.81 TSHR (0.44) ELANEKMT2ATSHRESR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9139672-B2 Polymerizable compound, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2015-09-22 US disclosed
US-9139672-B2 Polymerizable compound, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2015-09-22 US disclosed
US-20140346399-A1 POLYMERIZABLE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-11-27 US disclosed
US-20140346399-A1 POLYMERIZABLE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-11-27 US disclosed