Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16265691 | 0.92 | CYP2D6 (0.31) | CYP2D6 | |
| SCHEMBL16265615 | 0.88 | CYP3A4 (0.38) | CYP2D6ALDH1A1PIK3CDDRD3CHRM2 | |
| SCHEMBL16265832 | 0.86 | ALDH1A1 (0.36) | CYP2D6ALDH1A1PIK3CDBRD4PADI1 | |
| SCHEMBL16265706 | 0.83 | CYP2D6 (0.31) | CYP2D6PADI1PADI4DRD3CHRM2 | |
| SCHEMBL16265733 | 0.82 | ALDH1A1 (0.35) | CYP2D6ALDH1A1PIK3CDBRD4PADI1 | |
| SCHEMBL16266010 | 0.81 | ALDH1A1 (0.40) | CYP2D6ALDH1A1PIK3CDBRD4PADI1 | |
| SCHEMBL16265992 | 0.80 | CYP3A4 (0.36) | ALDH1A1 | |
| SCHEMBL12285113 | 0.79 | KDM4E (0.40) | CYP2D6ALDH1A1PIK3CDPADI1PADI4 | |
| SCHEMBL16265668 | 0.78 | ALDH1A1 (0.31) | CYP2D6ALDH1A1PIK3CDPADI1PADI4 | |
| SCHEMBL16265872 | 0.78 | PIK3CD (0.37) | CYP2D6ALDH1A1PIK3CDBRD4PADI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2808329-B1 | Silyl-Protected Nitrogen-Containing Cyclic Compounds and their method of preparation | SHINETSU CHEMICAL CO (JP) | 2018-09-26 | — | — | EP | disclosed |
| US-9233988-B2 | Silyl-protected nitrogen-containing cyclic compounds and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-01-12 | — | — | US | disclosed |
| CN-104211725-A | Silyl-protected nitrogen-containing cyclic compounds and making method | SHINETSU CHEMICAL CO | 2014-12-17 | — | — | CN | disclosed |
| US-20140357862-A1 | SILYL-PROTECTED NITROGEN-CONTAINING CYCLIC COMPOUNDS AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-12-04 | — | — | US | disclosed |
| EP-2808329-A1 | Silyl-Protected Nitrogen-Containing Cyclic Compounds and Making Method | Shin-Etsu Chemical Co., Ltd. (JP) | 2014-12-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357862-A1 | SILYL-PROTECTED NITROGEN-CONTAINING CYCLIC COMPOUNDS AND MAKING METHOD | PRMT9, CCNO, IPO9 | CYP2D6 4195/4885ALDH1A1 3666/4885PIK3CD 2796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.