Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 13/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL217714 | 0.84 | ALDH1A3 (0.37) | ALDH1A3ALDH1A1SLC2A1ALDH1A2PDGFRB | |
| SCHEMBL3435794 | 0.70 | NR4A2 (0.52) | ALDH1A3ALDH1A1SLC2A1ALDH1A2PDGFRB | |
| SCHEMBL217708 | 0.70 | ALDH1A3 (0.42) | ALDH1A3ALDH1A1SLC2A1ALDH1A2PDGFRB | |
| Hydrochloric Acid SCHEMBL218759 | 0.69 | ALDH1A3 (0.41) | ALDH1A3ALDH1A1SLC2A1ALDH1A2PDGFRB | |
| SCHEMBL3411468 | 0.68 | NR4A2 (0.67) | ALDH1A3ALDH1A1SLC2A1ALDH1A2NR4A2 | |
| SCHEMBL3430103 | 0.67 | NR4A2 (0.39) | ALDH1A3ALDH1A1SLC2A1ALDH1A2ADORA2A | |
| SCHEMBL217710 | 0.66 | NR4A2 (0.40) | ALDH1A3ALDH1A1SLC2A1ALDH1A2PDGFRB | |
| SCHEMBL3432955 | 0.66 | NR4A2 (0.65) | ALDH1A3ALDH1A1SLC2A1ALDH1A2NR4A2 | |
| SCHEMBL219947 | 0.66 | L3MBTL1 (0.39) | ALDH1A3ALDH1A1SLC2A1ALDH1A2NR4A2 | |
| SCHEMBL3430232 | 0.66 | LRRK2 (0.39) | ALDH1A1NR4A2NPC1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262804-B1 | POLYSUBSTITUTED DERIVATIVES OF 6-HETEROARYL-IMIDAZO[L,2- A] PYRIDINES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2014-12-03 | — | — | EP | disclosed |