Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11135159 | 0.84 | MAPT (0.40) | CYP2A6CYP1A2HTR2ANQO1L3MBTL1 | |
| SCHEMBL23846030 | 0.84 | CYP2A6 (0.38) | CYP2A6CYP1A2HTR2ANQO1L3MBTL1 | |
| SCHEMBL6036924 | 0.84 | CYP2A6 (0.45) | CYP2A6CYP1A2HTR2ANQO1L3MBTL1 | |
| SCHEMBL168894 | 0.83 | HTR2A (0.60) | CYP2A6CYP1A2HTR2AL3MBTL1ALDH1A1 | |
| SCHEMBL30992096 | 0.83 | HTR2A (0.60) | CYP2A6CYP1A2HTR2AL3MBTL1ALDH1A1 | |
| SCHEMBL11430395 | 0.82 | MAPT (0.39) | CYP2A6CYP1A2HTR2ANQO1L3MBTL1 | |
| SCHEMBL16267118 | 0.82 | ALDH1A1 (0.53) | CYP2A6CYP1A2HTR2ANQO1L3MBTL1 | |
| SCHEMBL9137780 | 0.81 | CYP1A2 (0.44) | CYP2A6CYP1A2HTR2ANQO1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL28993836 | 0.81 | HTR2A (0.58) | CYP2A6CYP1A2HTR2AL3MBTL1ALDH1A1 | |
| SCHEMBL5748818 | 0.80 | CYP1A2 (0.42) | CYP2A6CYP1A2HTR2ANQO1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9067857-B2 | Fluorine-containing aromatic compound and manufacturing method therefor | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-06-30 | — | — | US | disclosed |
| US-20140357906-A1 | FLUORINE-CONTAINING AROMATIC COMPOUND AND MANUFACTURING METHOD THEREFOR | AGC Inc. (JP) | 2014-12-04 | — | — | US | disclosed |
| CN-104114522-A | Fluorine-containing aromatic compound and manufacturing method therefor | ASAHI GLASS CO LTD | 2014-10-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357906-A1 | FLUORINE-CONTAINING AROMATIC COMPOUND AND MANUFACTURING METHOD THEREFOR | AFF1, AFF2, AFF4 | CYP2A6 1987/4885CYP1A2 172/4885HTR2A 3343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.