SCHEMBL16267653

SCHEMBL16267653

CC1(C)c2cccc3ccc4cc(N)cc1c4c23

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
HSD17B10 Q99714 4/20 0.36
CYP3A4 P08684 3/20 0.36
RAD52 P43351 1/20 0.36
MPO P05164 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
ALOX15 P16050 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
HBB P68871 1/20 0.35
HIF1A Q16665 1/20 0.35
TYMS P04818 1/20 0.35
CYP1A2 P05177 3/20 0.34
CYP1A1 P04798 2/20 0.34
CYP1B1 Q16678 2/20 0.34
HPGD P15428 2/20 0.34
TSHR P16473 1/20 0.34
CYP2D6 P10635 1/20 0.32
FTO Q9C0B1 1/20 0.32
MEN1 O00255 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31395712 0.82 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP3A4RAD52TDP1
SCHEMBL31413670 0.80 ALDH1A1 (0.48) ALDH1A1HSD17B10CYP3A4RAD52TDP1
SCHEMBL31413671 0.80 ALDH1A1 (0.48) ALDH1A1HSD17B10CYP3A4RAD52TDP1
SCHEMBL12982875 0.79 NPSR1 (0.40) ALDH1A1HSD17B10CYP3A4RAD52TDP1
SCHEMBL16271391 0.76 ALDH1A1 (0.37) ALDH1A1HSD17B10CYP3A4RAD52TDP1
SCHEMBL5574510 0.76 CYP3A4 (0.61) ALDH1A1HSD17B10CYP3A4MPOTDP1
SCHEMBL17849698 0.72 MAOB (0.34) ALDH1A1TYMSMAOAMAPK1
SCHEMBL12982551 0.72 LIPG (0.47) TYMSCYP1A1CYP1B1
SCHEMBL17301455 0.72 ALDH1A1 (0.46) ALDH1A1HSD17B10CYP3A4RAD52TDP1
SCHEMBL13888836 0.72 MAOB (0.34) ALDH1A1TYMSMAOAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022129116-A1 INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
WO-2022129114-A1 NITROGENOUS COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
WO-2022129113-A1 NITROGENOUS HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
US-9876176-B2 Aryl amine condensed cyclic compound comprising pyrene moieties and organic light-emitting diode (OLED) including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-01-23 US disclosed
US-20140353617-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-12-04 US disclosed