SCHEMBL1626995

SCHEMBL1626995

Cc1cc(C(C)(C)C)c(OC(C[Al])Oc2c(C(C)(C)C)cc(C)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 1/20 0.41
CA2 P00918 1/20 0.41
POLB P06746 1/20 0.41
TYR P14679 1/20 0.41
HSPA5 P11021 1/20 0.38
CYP2D6 P10635 2/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
HIF1A Q16665 2/20 0.37
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3678171 0.85 CYP1A2 (0.33) CYP3A4CYP2C9CYP2C19
SCHEMBL1626990 0.81 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL1561783 0.80 CYP3A4 (0.35) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL8905555 0.79 CA2 (0.39) SMN1; SMN2ALDH1A1CA2
SCHEMBL29534661 0.79 SMN1; SMN2 (0.45) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL28034278 0.76 SMN1; SMN2 (0.50) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL1033902 0.75 SMN1; SMN2 (0.45) SMN1; SMN2ALDH1A1CA2POLBTYR
Hydrochloric Acid SCHEMBL27786111 0.74 SMN1; SMN2 (0.48) SMN1; SMN2ALDH1A1CA2POLBTYR
Hydrochloric Acid SCHEMBL10482156 0.74 SMN1; SMN2 (0.48) SMN1; SMN2ALDH1A1CA2POLBTYR
Hydrochloric Acid SCHEMBL27797444 0.74 SMN1; SMN2 (0.48) SMN1; SMN2ALDH1A1CA2POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2099833-B1 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORP (US) 2015-11-11 EP claimed
US-8501655-B2 thermal stability, high catalyst activity; Bronsted acidic cation such as ionic compound formed from pentafluorophenol and dimethylaniline, and aluminate anion chemically bonded to a carrier ALBEMARLE CORPORATION (US) 2013-08-06 US claimed
US-7928172-B2 Catalyst activators, processes for making same, and use thereof in catalysts and polymerization of olefins ALBEMARLE CORPORATION (US) 2011-04-19 US claimed
US-20100093958-A1 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS W. R. GRACE & CO.-CONN. 2010-04-15 US claimed
US-20100029470-A1 Catalyst Activators, Processes for Making Same, And Use Thereof In Catalysts And Polymerization Of Olefins ALBENARLE CORPORATION (US) 2010-02-04 US claimed
EP-2099832-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS Albermarle Corporation (US) 2009-09-16 EP claimed
EP-2099833-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS Albermarle Corporation (US) 2009-09-16 EP claimed
WO-2008076632-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORPORATION (US) 2008-06-26 WO claimed
WO-2008036594-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORPORATION (US) 2008-03-27 WO claimed
US-20240228682-A1 POLYETHYLENE COPOLYMER WITH BROAD SHORT CHAIN BRANCHING DISTRIBUTION W.R. GRACE & CO.-CONN. (US) 2024-07-11 US disclosed
EP-4337703-A1 POLYETHYLENE COPOLYMER WITH BROAD SHORT CHAIN BRANCHING DISTRIBUTION W. R. Grace & Co.-Conn (US) 2024-03-20 EP disclosed
CN-117616055-A Polyethylene copolymers with broad short chain branching distribution 格雷斯公司 2024-02-27 CN disclosed
WO-2022241225-A1 POLYETHYLENE COPOLYMER WITH BROAD SHORT CHAIN BRANCHING DISTRIBUTION W.R. GRACE & CO.-CONN. (US) 2022-11-17 WO disclosed
EP-2195112-B1 ALUMINOXANE CATALYST ACTIVATORS DERIVED FROM DIALKYLALUMINUM CATION PRECURSOR AGENTS AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORP (US) 2017-03-01 EP disclosed
EP-2084193-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS Albermarle Corporation (US) 2009-08-05 EP disclosed
WO-2009029857-A1 ALUMINOXANE CATALYST ACTIVATORS DERIVED FROM DIALKYLALUMINUM CATION PRECURSOR AGENTS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORPORATION (US) 2009-03-05 WO disclosed
US-20090062492-A1 Aluminoxane Catalyst Activators Derived From Dialkylaluminum Cation Precursor Agents, Processes For Making Same, And Use Thereof In Catalysts And Polymerization Of Olefins ALBEMARLE CORPORATION (US) 2009-03-05 US disclosed
WO-2008076632-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORPORATION (US) 2008-06-26 WO disclosed
WO-2008036594-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORPORATION (US) 2008-03-27 WO disclosed
WO-2008036591-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORPORATION (US) 2008-03-27 WO disclosed