Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27797444 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Hydrochloric Acid SCHEMBL10482156 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL28034278 | 0.98 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Hydrochloric Acid SCHEMBL28141949 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL2868169 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL11647740 | 0.78 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL4564513 | 0.77 | CYP2D6 (0.49) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Hydrochloric Acid SCHEMBL6916542 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Hydrochloric Acid SCHEMBL27921674 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Hydrochloric Acid SCHEMBL3149546 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1CA2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106519533-A | Preparation method of polydicyclopentadiene/modified polystyrene composite material | 郑州峰泰纳米材料有限公司 | 2017-03-22 | — | — | CN | claimed |
| CN-103665700-B | A kind of Polydicyclopentadiencomposite composite material and preparation method thereof | HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-10-07 | — | — | CN | claimed |
| CN-103665700-A | Polydicyclopentadiene composite material and preparation method thereof | UNIV HENAN SCIENCE & TECH | 2014-03-26 | — | — | CN | claimed |
| CN-109943024-B | Curing resin for preparing carbon fiber composite material and application thereof | 上海化工研究院有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-106519533-A | Preparation method of polydicyclopentadiene/modified polystyrene composite material | 郑州峰泰纳米材料有限公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-103665700-B | A kind of Polydicyclopentadiencomposite composite material and preparation method thereof | HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-10-07 | — | — | CN | disclosed |
| CN-103665700-B | A kind of Polydicyclopentadiencomposite composite material and preparation method thereof | HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-10-07 | — | — | CN | disclosed |
| CN-103665700-A | Polydicyclopentadiene composite material and preparation method thereof | UNIV HENAN SCIENCE & TECH | 2014-03-26 | — | — | CN | disclosed |
| CN-101597351-B | Preparation method of polydicyclopentadiene/rubber in-situ polymerization blending composite material | UNIV HENAN SCIENCE & TECH | 2011-09-28 | — | — | CN | disclosed |
| CN-101597351-A | The polydicyclopentadien//rubber in-situ polymerization blending composite material preparation method | UNIV HENAN SCIENCE & TECH (CN) | 2009-12-09 | — | — | CN | disclosed |