Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 10/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29436267 | 0.81 | MAPT (0.49) | SLC6A9SMONPC1 | |
| SCHEMBL12643221 | 0.81 | MAPT (0.49) | SLC6A9SMONPC1 | |
| SCHEMBL32672556 | 0.81 | SMO (0.44) | SLC6A9KCNH2SMONPC1RAB9A | |
| SCHEMBL32672541 | 0.81 | SLC6A9 (0.44) | SLC6A9KCNH2SMOGPR55CYP2C9 | |
| SCHEMBL30511079 | 0.79 | GAA (0.53) | SLC6A9KCNH2SMONPC1RAB9A | |
| SCHEMBL17636193 | 0.79 | GAA (0.53) | SLC6A9KCNH2SMONPC1RAB9A | |
| SCHEMBL32672593 | 0.76 | SMO (0.47) | SLC6A9SMONPC1CYP2C9HDAC1 | |
| SCHEMBL32672552 | 0.75 | SMO (0.47) | SLC6A9SMONPC1CYP2C9HDAC1 | |
| SCHEMBL19852721 | 0.75 | SMO (0.49) | SMONPC1RAB9ACYP2C9HDAC1 | |
| SCHEMBL12643198 | 0.74 | KMT2A (0.49) | SLC6A9KCNH2NPC1CYP2C9HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8901129-B2 | Methods of facilitating neural cell survival using GDNF family ligand (GFL) mimetics or RET signaling pathway activators | GENECODE AS (EE) | 2014-12-02 | — | — | US | disclosed |