Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30511079 | 0.83 | GAA (0.53) | SMOCYP2C9HDAC1HDAC6NPC1 | |
| SCHEMBL17636193 | 0.83 | GAA (0.53) | SMOCYP2C9HDAC1HDAC6NPC1 | |
| SCHEMBL30691928 | 0.81 | NPC1 (0.48) | SMOCYP2C9HDAC1HDAC6NPC1 | |
| SCHEMBL32672556 | 0.80 | SMO (0.44) | SMOCYP2C9HDAC1HDAC6NPC1 | |
| SCHEMBL32672541 | 0.80 | SLC6A9 (0.44) | SMOCYP2C9HDAC1HDAC6HCRTR1 | |
| SCHEMBL29436267 | 0.80 | MAPT (0.49) | SMONPC1MAPTALDH1A1MEN1 | |
| SCHEMBL32672593 | 0.80 | SMO (0.47) | SMOCYP2C9HDAC1HDAC6NPC1 | |
| SCHEMBL12643221 | 0.80 | MAPT (0.49) | SMONPC1MAPTALDH1A1MEN1 | |
| SCHEMBL32672552 | 0.79 | SMO (0.47) | SMOCYP2C9HDAC1HDAC6NPC1 | |
| SCHEMBL14668242 | 0.77 | CYP2C9 (0.48) | CYP2C9HDAC1HDAC6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210244728-A1 | Method of treating peripheral neuropathy | CHEMEDEST LTD (EE) | 2021-08-12 | — | — | US | disclosed |
| US-20200113895-A1 | Method of treating peripheral neuropathy | CHEMEDEST LTD. (EE) | 2020-04-16 | — | — | US | disclosed |
| US-20180036305-A1 | Method of treating peripheral neuropathy | CHEMEDEST LTD. (EE) | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210244728-A1 | Method of treating peripheral neuropathy | GFRA3, GFRA2, GFRA1 | SMO 3514/4885CYP2C9 3497/4885HDAC1 4532/4885 |
| US-20180036305-A1 | Method of treating peripheral neuropathy | GFRA3, GFRA2, GAP43 | SMO 3421/4885CYP2C9 4189/4885HDAC1 4230/4885 |
| US-20200113895-A1 | Method of treating peripheral neuropathy | GFRA3, GFRA1, GFRA2 | SMO 3540/4885CYP2C9 3683/4885HDAC1 4451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.