Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | CHAT | P28329 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31550573 | 1.00 | MAPT (0.48) | MAPTLMNANPC1GFERHSD17B10 | |
| SCHEMBL31550565 | 1.00 | MAPT (0.48) | MAPTLMNANPC1GFERHSD17B10 | |
| SCHEMBL32689415 | 0.93 | MAPT (0.49) | MAPTLMNANPC1GFERHSD17B10 | |
| SCHEMBL29069515 | 0.91 | CHEK1 (0.43) | MAPTLMNACYP1A1CYP1B1CYP1A2 | |
| SCHEMBL29069512 | 0.91 | CHEK1 (0.43) | MAPTLMNACYP1A1CYP1B1CYP1A2 | |
| SCHEMBL9099842 | 0.88 | ALDH1A1 (0.45) | HSD17B10CYP1A1CYP1B1CYP1A2GUSB | |
| SCHEMBL9407210 | 0.88 | ALDH1A1 (0.45) | HSD17B10CYP1A1CYP1B1CYP1A2GUSB | |
| SCHEMBL31550572 | 0.84 | RELA (0.46) | LMNANPC1HSD17B10KDM4ECYP1A1 | |
| SCHEMBL131581 | 0.84 | RELA (0.46) | LMNANPC1HSD17B10KDM4ECYP1A1 | |
| SCHEMBL131580 | 0.84 | RELA (0.46) | LMNANPC1HSD17B10KDM4ECYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140357503-A1 | METHOD AND ARRAY FOR IDENTIFYING HISTONE-CODE-RELATED ANALYTES | UVIC INDUSTRY PARTNERSHIPS INC. (CA) | 2014-12-04 | — | — | US | disclosed |